A placebo-controlled randomized clinical trial of naltrexone in the context of different levels of psychosocial intervention.

Author: DackisCharles, DundonWilliam, GaritiPeter, GelfandLois, KampmanKyle M, LynchKevin G, O'BrienCharles P, OslinDavid W, PettinatiHelen M, Ten HaveThomas, VolpicelliJoseph R, WortmanShoshana

Paper Details 
Original Abstract of the Article :
Naltrexone is approved for the treatment of alcohol dependence when used in conjunction with a psychosocial intervention. This study was undertaken to examine the impact of 3 types of psychosocial treatment combined with either naltrexone or placebo treatment on alcohol dependency over 24 weeks of t...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/18540910

データ提供:米国国立医学図書館(NLM)

Naltrexone: A Promising Ally in the Battle Against Alcohol Dependence

The field of alcohol dependence treatment is an ever-evolving landscape, with researchers constantly seeking new strategies to help those struggling with this challenging condition. This study dives deep into the effectiveness of naltrexone, a medication commonly prescribed for alcohol dependence, when combined with different forms of psychosocial intervention. Like a skilled camel navigating a vast desert, this study explores the intricate interactions between medication and therapy, seeking the most effective path to recovery. The researchers employed a randomized clinical trial design, a rigorous approach that allows them to separate the effects of naltrexone from any placebo effects. They tested naltrexone against a placebo in three different groups: a Cognitive-Behavioral Therapy (CBT) group, a BRENDA (an intervention promoting pharmacotherapy) group, and a medication clinic model with limited therapeutic content.

Naltrexone and Psychosocial Therapy: A Dynamic Duo

The results of this study offer valuable insights into the complexities of alcohol dependence treatment. The researchers discovered that combining naltrexone with a psychosocial intervention, such as CBT or BRENDA, significantly improved outcomes compared to using naltrexone alone or relying solely on limited therapeutic support. This finding underscores the importance of a multi-pronged approach, much like a camel relying on both its strength and its endurance to conquer a challenging desert journey.

A Holistic Approach to Recovery

The study's findings highlight the potential of a holistic approach to treating alcohol dependence. By integrating both medication and psychosocial support, we can better address the multifaceted nature of this condition. This study encourages us to think beyond simply prescribing medication, emphasizing the importance of addressing underlying psychological and behavioral factors that contribute to alcohol dependence. Much like a camel navigating diverse terrains, we must adapt our approach to address the individual needs of each person seeking recovery.

Dr.Camel's Conclusion

This study provides valuable insights into the benefits of using naltrexone in conjunction with psychosocial interventions for alcohol dependence. The findings underscore the importance of a holistic approach to treatment, addressing both the biological and psychological aspects of this complex condition. This research also suggests that the type of psychosocial intervention employed can significantly influence treatment outcomes, highlighting the need for individualized care plans tailored to each patient's needs.

Date :
  1. Date Completed 2008-10-07
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

18540910

DOI: Digital Object Identifier

NIHMS315003

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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