Effect of doxazosin gastrointestinal therapeutic system as third-line antihypertensive therapy on blood pressure and lipids in the Anglo-Scandinavian Cardiac Outcomes Trial.

Author: , ChangChoon Lan, ChapmanNeil, DahlöfBjörn, PoulterNeil R, SeverPeter S, WedelHans

Paper Details 
Original Abstract of the Article :
BACKGROUND: The role of doxazosin in treatment of hypertension remains controversial. METHODS AND RESULTS: We evaluated the effects on blood pressure (BP) and biochemical parameters of doxazosin GITS (gastrointestinal therapeutic system) as a third-line antihypertensive agent among 10,069 participa...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1161/CIRCULATIONAHA.107.737957

データ提供:米国国立医学図書館(NLM)

Doxazosin: A Promising Third-Line Antihypertensive Agent

Hypertension, or high blood pressure, is a prevalent health concern that can significantly increase the risk of heart disease, stroke, and other cardiovascular complications. This research evaluates the efficacy and safety of doxazosin, an alpha-blocker, as a third-line antihypertensive agent. The study analyzed data from the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT-BPLA), a large-scale clinical investigation, to assess the effects of doxazosin on blood pressure and lipid profiles. Researchers found that doxazosin effectively reduced blood pressure and had modest favorable effects on lipid profiles, demonstrating its potential as a third-line antihypertensive agent.

Doxazosin's Effectiveness in Lowering Blood Pressure

The study's findings suggest that doxazosin is an effective third-line antihypertensive agent. The significant reduction in blood pressure observed in the study provides compelling evidence for its efficacy in managing hypertension. It's like discovering a hidden spring in a desert, providing a reliable source of relief for those seeking to lower their blood pressure.

Implications for Hypertension Management

This research highlights the potential of doxazosin as a valuable tool for managing hypertension. The study's findings encourage further investigation into its long-term efficacy and potential for improving cardiovascular health. It's like finding a new path through a desert, leading towards a healthier and more fulfilling life for those living with hypertension.

Dr. Camel's Conclusion

This research provides valuable insights into the efficacy and safety of doxazosin as a third-line antihypertensive agent. The study's findings suggest that doxazosin can effectively lower blood pressure and may offer a viable option for patients who have not achieved adequate control with other medications. It's like discovering a hidden oasis in a desert, offering a potential source of relief for those seeking to manage their hypertension.

Date :
  1. Date Completed 2008-09-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

18559700

DOI: Digital Object Identifier

10.1161/CIRCULATIONAHA.107.737957

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.