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Tacrolimus (FK506) for induction of remission in refractory ulcerative colitis.

Author: BaumgartDaniel C, FeaganBrian, MacdonaldJohn K

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Tacrolimus may be effective for short-term clinical improvement in patients with refractory ulcerative colitis, but more data are needed to determine its long-term efficacy and safety.
Paper Details　
Original Abstract of the Article :
BACKGROUND: There are a limited number of treatment options for patients with refractory ulcerative colitis. Animal models of inflammatory bowel disease and uncontrolled studies in humans suggest that tacrolimus may be effective treatment for ulcerative colitis. OBJECTIVES: This review aims to eval...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD007216

データ提供：米国国立医学図書館（NLM）

Tacrolimus for Refractory Ulcerative Colitis: A New Oasis in the Desert of Inflammatory Bowel Disease

Ulcerative colitis is a chronic inflammatory bowel disease that can be difficult to treat. This research explores the potential of tacrolimus, an immunosuppressant drug, for inducing remission in patients with refractory ulcerative colitis. It examines the efficacy and safety of tacrolimus in a randomized controlled trial, offering insights into its potential as a therapeutic option.

Tacrolimus: A Promising Treatment for Refractory Ulcerative Colitis

The study reveals that tacrolimus may be effective for short-term clinical improvement in patients with refractory ulcerative colitis. It highlights the potential of tacrolimus as a valuable treatment option for individuals who have not responded to other therapies. While more research is needed to confirm its long-term efficacy and safety, the findings offer a glimmer of hope for patients seeking relief from this debilitating condition.

Navigating the Desert of Inflammatory Bowel Disease: New Treatment Options

This research sheds light on the ongoing quest for new and effective treatments for ulcerative colitis. It underscores the importance of exploring innovative therapies for patients with refractory disease, offering hope for a future where more individuals can find lasting relief from this chronic condition.

Dr.Camel's Conclusion

This research provides a valuable insight into the vast desert of inflammatory bowel disease, exploring the potential of tacrolimus as a treatment for refractory ulcerative colitis. It encourages us to continue researching new and innovative therapies, offering patients hope for a future with improved treatment options and a better quality of life.

Date :
  1. Date Completed 2008-10-15
  2. Date Revised 2022-05-04
Further Info :

Pubmed ID

18646177

DOI: Digital Object Identifier

10.1002/14651858.CD007216

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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