Paper Details
- Home
- Paper Details
Clinical drugs that interact with St. John's wort and implication in drug development.
Author: DiYuan Ming, LiChun Guang, XueCharlie Changli, ZhouShu-Feng
Original Abstract of the Article :
St. John's wort (Hypericum perforatum, SJW) is one of the most commonly used herbal antidepressants for the treatment of minor to moderate depression. A major safety concern about SJW is its ability to alter the pharmacokinetics and/or clinical response of a variety of clinically important drugs tha...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/138161208784746798
データ提供:米国国立医学図書館(NLM)
St. John's Wort: A Double-Edged Sword in the Desert of Drug Interactions
St. John's wort, a popular herbal remedy for mild to moderate depression, has gained widespread use. However, its potential for drug interactions raises a critical question: Can this natural remedy safely coexist with other medications? This research explores the complex interplay between St. John's wort and a wide range of conventional drugs, including anticancer, anti-HIV, anti-inflammatory, antimicrobial, cardiovascular, central nervous system, hypoglycemic, immuno-modulating, oral contraceptive, proton pump inhibitor, respiratory, and statin medications.
Imagine a bustling marketplace in a desert oasis, where traders from different regions converge. This research, like a cautious traveler navigating this marketplace, aims to understand how the introduction of St. John's wort might impact the interactions between various medications.
A Complex Web of Interactions
This research identifies numerous interactions between St. John's wort and conventional drugs, highlighting the potential for both pharmacokinetic and pharmacodynamic changes. St. John's wort can induce the production of certain enzymes involved in drug metabolism, leading to alterations in drug levels and effectiveness. This emphasizes the importance of consulting a healthcare professional before using St. John's wort, particularly when already taking other medications.
Navigating the Desert of Medication Interactions
This study, like a signpost in the desert of drug interactions, provides crucial information for both healthcare providers and patients. It encourages a proactive approach to medication management, particularly when considering the use of herbal remedies like St. John's wort. Always consult your healthcare provider before introducing new medications, including herbal supplements, to your routine.
Dr.Camel's Conclusion
This research, like a vigilant camel crossing a vast desert landscape, emphasizes the importance of careful consideration when combining St. John's wort with other medications. It serves as a reminder that even seemingly natural remedies can have significant interactions with other drugs, potentially affecting their effectiveness and safety.
Date :
- Date Completed 2008-10-06
- Date Revised 2022-03-09
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.