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An open labeled, comparative clinical study on efficacy and tolerability of oral minipulse of steroid (OMP) alone, OMP with PUVA and broad / narrow band UVB phototherapy in progressive vitiligo.

Author: KarH K, RathNamita, SabhnaniSunil

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Narrow band UVB phototherapy was more effective than broad band UVB for treating vitiligo, and comparable to PUVA therapy. Oral minipulse steroid therapy had limited efficacy on its own.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Several modalities of treatment have been tried in vitiligo with varied results; however, Indian data on comparative studies of two or more therapies are limited. AIMS: We compared different phototherapy methods with an oral steroid as an adjunct to determine the method with the best to...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.4103/0378-6323.42905

データ提供：米国国立医学図書館（NLM）

Treating Vitiligo: A Comparative Study of Phototherapy and Oral Steroids

This research compares different [phototherapy] methods, with an adjunct of [oral minipulse of steroids (OMP)], in treating [vitiligo], a condition that causes depigmentation of the skin. The study included 86 patients with progressive vitiligo, randomly assigned to four different treatment groups.

A Desert of Skin Conditions: Comparing Phototherapy Approaches

The researchers found that [narrow band UVB (NB-UVB) and PUVA] showed comparable efficacy in treating vitiligo, with both showing greater improvement than [broad band UVB (BB UVB) or OMP alone]. This suggests that NB-UVB and PUVA may be more effective options for treating this condition.

Navigating the Options: Choosing the Right Treatment for Vitiligo

This research provides valuable insights into the effectiveness of different phototherapy approaches for treating vitiligo. It emphasizes the importance of selecting the most appropriate treatment based on individual patient needs and the potential benefits and risks associated with each approach. It's like choosing the right camel for a long journey in the desert, carefully considering the strengths and limitations of each option.

Dr.Camel's Conclusion

This study demonstrates the importance of exploring various treatment options when dealing with complex skin conditions. It highlights the potential of phototherapy as a valuable tool for managing vitiligo and suggests that NB-UVB and PUVA may offer more effective treatment options compared to other approaches.

Date :
  1. Date Completed 2009-02-10
  2. Date Revised 2019-11-11
Further Info :

Pubmed ID

18797057

DOI: Digital Object Identifier

10.4103/0378-6323.42905

Related Literature

Article Analysis
・Effective treatment of vitiligo
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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