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Eighteen months of drug treatment for depression: predicting relapse and recovery.

Author: FramptonChristopher M A, JoycePeter R, LutySuzanne E, MulderRoger T

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

While most patients with depression recovered within 6 months, 46% relapsed within a year. Relapse was associated with recurrent depression history, residual symptoms, a less sustained response to initial treatment, and personality disorder symptoms. Only 34% of patients who were depressed at 6 months recovered.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The clinically relevant outcomes in treating depression are persistent recovery, relapse, and treatment resistance. METHOD: 175 outpatients treated with antidepressants for 6 months were assessed for major depression. Those who had recovered were prospectively monitored for one year to ...See full text at original site
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引用元：
https://doi.org/10.1016/j.jad.2008.08.002

データ提供：米国国立医学図書館（NLM）

Relapse and Recovery in Depression: Navigating the Desert of Mental Illness

The [depression] desert is a challenging landscape, with [relapse] as common as a sandstorm. This study examines the factors that predict [relapse] and [recovery] in [patients treated for depression]. It's like studying the patterns of the desert winds to understand how they influence the journey of healing.

Understanding the Winds of Relapse

The study reveals that [relapse] is unfortunately common, even after [successful treatment]. It's like a desert wind that can easily sweep in and disrupt the fragile balance of recovery. The study identifies several factors that increase the risk of relapse, including [a history of recurrent depression], [residual depressive symptoms], and [a less sustained response to initial treatment]. These factors are like the desert's shifting sands, making it difficult to predict the course of recovery.

Navigating the Desert of Mental Illness

This research underscores the importance of [ongoing monitoring] and [sustained treatment efforts] for [patients with depression]. It's like a reminder that even after a sandstorm has passed, the desert's landscape can still be unpredictable. The study highlights the need for a collaborative approach between [patients] and [clinicians] to ensure that the journey through the desert of depression is as smooth and successful as possible.

Dr.Camel's Conclusion

The journey through the desert of depression is a long and winding one, with unexpected challenges along the way. This study reminds us that even after finding a temporary oasis, it's crucial to stay vigilant and seek continued support. It's a testament to the resilience of the human spirit and the importance of ongoing care in navigating the complexities of mental health.

Date :
  1. Date Completed 2009-07-22
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

18805590

DOI: Digital Object Identifier

10.1016/j.jad.2008.08.002

Related Literature

Article Analysis
・Effective treatment of depression
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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