Comparative study of the effects of gentamicin, neomycin, streptomycin and ofloxacin antibiotics on sperm parameters and testis apoptosis in rats.

Author: KhakiAmir Afshin, KhakiArash, NikmaneshMahdad, NouriMohammad, NovinMarefat Ghaffari, SanatiEhsan

Paper Details 
Original Abstract of the Article :
The aim of this study was to investigate the comparative effects of aminoglycosides and fluoroquinolones on testis apoptosis and sperm parameters in rats. Fifty male Wistar rats were randomly divided into control (n = 10) and experimental (n = 40) groups. The experimental groups subdivided into four...See full text at original site
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引用元:
https://doi.org/10.3923/pjbs.2008.1683.1689

データ提供:米国国立医学図書館(NLM)

The Impact of Antibiotics on Sperm Parameters and Testis Apoptosis

Antibiotics are widely used to treat bacterial infections, but their potential impact on male reproductive health is an area of growing concern. This study investigates the comparative effects of aminoglycosides (gentamicin, neomycin, streptomycin) and fluoroquinolones (ofloxacin) on sperm parameters and testis apoptosis in rats.

Antibiotics and Male Fertility: A Complex Relationship

The study found that all antibiotics tested significantly decreased sperm count, viability, and motility, suggesting a negative impact on sperm quality. The researchers also observed increased testis apoptosis in all experimental groups, indicating potential damage to testicular tissue. It's like a desert oasis facing a prolonged drought – the lack of essential nutrients and moisture can lead to a decline in vitality and potential harm to the ecosystem.

Minimizing Risks and Protecting Male Fertility

This study highlights the need for caution when prescribing antibiotics to men, particularly those of reproductive age. It's crucial to consider the potential impact on male fertility and to explore alternative treatment options whenever possible. Think of it as a wise camel caravan – they carefully choose their route to avoid dangerous areas and conserve their resources, just as we should be mindful of the potential risks and consequences of antibiotic use.

Dr.Camel's Conclusion

This research provides valuable insights into the potential impact of antibiotics on male reproductive health. It underscores the importance of considering the broader effects of medication, not just on the target infection but also on other bodily systems. It's a reminder that the quest for effective treatments must be balanced with a commitment to safeguarding overall health and well-being.

Date :
  1. Date Completed 2008-10-17
  2. Date Revised 2019-09-07
Further Info :

Pubmed ID

18819619

DOI: Digital Object Identifier

10.3923/pjbs.2008.1683.1689

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PICO Info
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Languages

English

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