Effects of meclofenamate on natural killer cell activity.

Author: AmbrusJ, ChadhaK C, HammadA, StadlerI

Paper Details 
Original Abstract of the Article :
The effect of meclofenamate on natural killer cell activity was studied in a four hour 51Cr release assay. Meclofenamate, a nonsteroidal anti-inflammatory drug, had no effect on natural killer cell activity when added to the mixture of target (K562) and effector (peripheral blood mononuclear) cells ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/1882128

データ提供:米国国立医学図書館(NLM)

Meclofenamate and Natural Killer Cell Activity: A Surprising Twist

The world of [Immunology] is a fascinating one, with intricate interactions between different cells and molecules. This study explores the effect of [Meclofenamate], a nonsteroidal anti-inflammatory drug, on [Natural Killer (NK) cell activity]. It's like a desert explorer uncovering a hidden spring: Meclofenamate, initially thought to be a simple anti-inflammatory agent, reveals an unexpected effect on NK cells.

Meclofenamate: A New Role for an Old Drug

The study found that [Meclofenamate] did not directly affect NK cell activity when added to the mixture of target and effector cells. However, a surprising observation emerged when target cells were pre-treated with Meclofenamate: NK cell activity significantly increased. It's like a desert mirage: Meclofenamate, initially thought to have no impact on NK cells, unveils a hidden influence when applied to target cells.

The Potential for New Therapeutic Strategies

This research raises intriguing possibilities for the role of [Meclofenamate] in immune regulation. It suggests that Meclofenamate might have potential therapeutic applications beyond its traditional anti-inflammatory properties. Further research could explore its role in enhancing NK cell activity for targeted cancer therapy or immune modulation.

Dr.Camel's Conclusion

This study offers a fascinating glimpse into the unexpected interactions between drugs and immune cells. Meclofenamate, a well-known anti-inflammatory agent, reveals a new role in boosting NK cell activity. The study's findings open doors for further investigation and potential new therapeutic strategies, expanding our understanding of the intricate dance between drugs and the immune system.

Date :
  1. Date Completed 1991-10-01
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

1882128

DOI: Digital Object Identifier

1882128

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.