Adverse radiation effects after radiosurgery may benefit from oral vitamin E and pentoxifylline therapy: a pilot study.

Author: FlickingerJohn C, KanaanHilal, KondziolkaDouglas, LunsfordL Dade, WilliamsonRichard

Paper Details 
Original Abstract of the Article :
Although uncommon, adverse radiation effects (ARE) are a potentially serious side effect of brain stereotactic radiosurgery (SRS). Corticosteroids are used to treat suspected ARE but side effects may be significant after long-term usage. Oral pentoxifylline (Ptx) and vitamin E therapy (VitE) are rep...See full text at original site
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引用元:
https://doi.org/10.1159/000163557

データ提供:米国国立医学図書館(NLM)

Radiation Effects After Radiosurgery: Exploring Alternative Treatment Options

[Brain stereotactic radiosurgery (SRS)] is a precise form of radiation therapy used to treat brain tumors and other conditions. While generally effective, some patients may experience [adverse radiation effects (ARE)]. This study investigates the potential benefits of [oral vitamin E and pentoxifylline therapy] in managing ARE after SRS. The researchers aimed to find alternative treatment options for ARE, particularly those that might reduce the need for long-term corticosteroid use.

Vitamin E and Pentoxifylline: Potential Allies Against Radiation Effects

The study found that [oral vitamin E and pentoxifylline therapy] showed promise in managing ARE after SRS. While further research is needed to confirm these findings, the preliminary results suggest that this combination therapy could be a valuable option for patients experiencing ARE, potentially reducing their need for corticosteroids.

Managing Radiation Effects: Expanding the Treatment Arsenal

This pilot study provides encouraging evidence for the potential benefits of [oral vitamin E and pentoxifylline therapy] in managing ARE after SRS. The findings suggest that this combination therapy could offer a more effective and potentially safer alternative to long-term corticosteroid use. This research could pave the way for more comprehensive and individualized treatment strategies for patients experiencing ARE following SRS.

Dr. Camel's Conclusion

The journey of cancer treatment can be long and arduous, like crossing a vast desert. This study explores the potential of [oral vitamin E and pentoxifylline therapy] as a refreshing oasis, offering hope for patients experiencing [adverse radiation effects (ARE)] after [brain stereotactic radiosurgery (SRS)]. The findings encourage us to consider this alternative treatment option, potentially improving the well-being of patients undergoing radiation therapy.

Date :
  1. Date Completed 2009-06-09
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

18854663

DOI: Digital Object Identifier

10.1159/000163557

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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