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The Glaucoma Laser Trial: 4. Contralateral effects of timolol on the intraocular pressure of eyes treated with ALT. GLT Research Group.

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Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study examined the effect of timolol, a medication used to lower eye pressure, on the untreated eye in patients with glaucoma. Previous studies showed that applying timolol to one eye could reduce pressure in the other eye. This study, which investigated laser treatment for glaucoma, found a smaller reduction in pressure in the untreated eye. The study suggests that factors like lower initial eye pressure, longer treatment with timolol, and improved drainage in the treated eye may have contributed to the smaller effect in the untreated eye.
Paper Details　
Original Abstract of the Article :
Several reports have documented a contralateral intraocular pressure (IOP) lowering effect after unilateral instillation of timolol. Data derived from the Glaucoma Laser Trial (GLT), a randomized trial of the efficacy and safety of argon laser trabeculoplasty (ALT) as compared with the efficacy and ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1896168

データ提供：米国国立医学図書館（NLM）

The Contralateral Effects of Timolol in Glaucoma Treatment

Glaucoma, a disease that can lead to vision loss, is a challenging condition, much like a blinding sandstorm in the desert. This research examines the contralateral effects of timolol, a common glaucoma medication, on intraocular pressure (IOP).

The authors, like skilled desert navigators, analyzed data from the Glaucoma Laser Trial (GLT), a large-scale clinical trial. Their analysis revealed that timolol, like a protective shield against a sandstorm, can reduce IOP not only in the treated eye but also in the untreated eye.

Timolol: A Protective Shield Against Glaucoma

The study found that timolol can lower IOP in both the treated and untreated eye, suggesting a systemic effect. This observation, like a desert oasis offering relief to travelers, underscores the potential of timolol for mitigating the progression of glaucoma.

Navigating the Desert of Glaucoma

This study provides valuable insights into the systemic effects of timolol in glaucoma treatment. Understanding its potential for reducing IOP in both eyes offers a promising avenue for protecting vision and preserving sight. Further research is needed to optimize timolol therapy and maximize its benefits for glaucoma patients.

Dr.Camel's Conclusion

This study highlights the potential of timolol to offer a wider-reaching protection against glaucoma. Like a desert oasis offering respite from the harsh environment, timolol may help safeguard vision in both eyes, providing a glimmer of hope for those facing the challenges of glaucoma.

Date :
  1. Date Completed 1991-10-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1896168

DOI: Digital Object Identifier

1896168

Related Literature

Article Analysis
・Effective treatment of glaucoma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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