Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars.

Author: AsilianA, DaroughehA, ShariatiF

Paper Details 
Original Abstract of the Article :
BACKGROUND: Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients. METHODS: In this 12-week, double-blind, clinical trial, 40 patients were randomized into two study groups. Patients in group 1 were given intr...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2230.2007.02631.x

データ提供:米国国立医学図書館(NLM)

Keloid and Hypertrophic Scars: A Persistent Problem

Keloids and hypertrophic scars are unsightly and often painful growths of dermal collagen that can significantly impact a person's quality of life. This research explores the effectiveness of two treatment options: intralesional triamcinolone acetonide (TAC) and a combination of TAC and 5-fluorouracil (5-FU). The study found that both treatments resulted in improvements in various parameters, but the combination of TAC and 5-FU yielded significantly better results in terms of patient satisfaction and overall improvement. These findings suggest that the combination therapy could be a more effective and acceptable treatment option for patients with keloids and hypertrophic scars.

The Promise of Combination Therapy

The study's findings highlight the potential benefits of combining TAC and 5-FU for the treatment of keloids and hypertrophic scars. This combination therapy appears to offer a more comprehensive approach, potentially leading to better outcomes and improved patient satisfaction. Further research is needed to confirm these findings and evaluate the long-term efficacy and safety of this combination therapy.

Navigating the Landscape of Scar Treatment

Imagine keloids and hypertrophic scars as towering, imposing mountains, a constant reminder of past injuries. This research, like a skilled mountaineer, explores different paths to conquer these formidable challenges. The researchers found that a combination of TAC and 5-FU, like a well-equipped expedition team, offers a more effective and satisfying approach, potentially leading to better outcomes and a more peaceful landscape.

Dr. Camel's Conclusion

Keloid and hypertrophic scars can significantly impact a person's quality of life, but research continues to offer new avenues for treatment. This study provides encouraging evidence for the effectiveness of combination therapy with TAC and 5-FU, potentially offering a more effective and acceptable solution for patients. By embracing innovative approaches and refining our strategies, we can continue to navigate the challenging landscape of scar treatment and strive towards better outcomes for all.

Date :
  1. Date Completed 2009-04-14
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

19018794

DOI: Digital Object Identifier

10.1111/j.1365-2230.2007.02631.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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