Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety.

Author: GonzalezRobert, Harnett-SheehanKathy, JanavsJuris, KeckPaul E, McElroySusan L, RogersJamison, SheehanDavid V, ShivakumarGeetha, SuppesTrisha

Paper Details 
Original Abstract of the Article :
BACKGROUND: The treatment of bipolar disorder is often complicated by the presence of a co-occuring anxiety disorder. Although second generation antipsychotics are being used with increasing frequency in bipolar patients, their anxiolytic effects have not been well studied in this population. METHO...See full text at original site
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引用元:
https://doi.org/10.1016/j.jad.2008.10.005

データ提供:米国国立医学図書館(NLM)

Risperidone for Bipolar Anxiety: A Desert of Results

In the vast and often perplexing landscape of mental health research, we're constantly searching for effective treatments for complex conditions. This study ventures into the desert of bipolar disorder, a condition that's frequently accompanied by the thirsty pangs of anxiety. The researchers set out to explore the potential of risperidone, a medication known for its calming effect, as a treatment for anxiety in individuals with bipolar disorder. They embarked on a grand expedition – an 8-week, double-blind, placebo-controlled, randomized clinical trial involving 111 individuals. The researchers used a variety of tools, including the Clinician Global Improvement-21 Anxiety scale, the Hamilton Anxiety Scale, and the Sheehan Panic Disorder Scale, to measure the effects of risperidone compared to a placebo. Their journey revealed a rather dry and disappointing outcome: risperidone didn't prove to be more effective than a placebo in relieving anxiety in this population.

Risperidone: A Mirage in the Desert of Bipolar Anxiety?

The results of this research suggest that risperidone, at least in the doses studied, may not be the oasis we were hoping for when it comes to treating anxiety in patients with bipolar disorder. While risperidone was generally well tolerated, the researchers noted that the group receiving risperidone had a higher proportion of individuals with mixed states and a history of panic disorder. This raises the possibility that these factors might have influenced the results, suggesting that further research is needed to understand the role of risperidone in treating anxiety in the context of bipolar disorder.

Navigating the Desert: What to Do If You Have Bipolar Disorder and Anxiety?

If you are struggling with bipolar disorder and anxiety, it's important to remember that you are not alone in this arid landscape. There are many treatment options available, and finding the right path is crucial. This research emphasizes the need to continue exploring other treatments, such as second-generation antipsychotics and mood stabilizers, for anxiety in individuals with bipolar disorder. Don't give up hope - the oasis of relief is out there!

Dr.Camel's Conclusion

This study highlights the challenges we face in treating mental illnesses, particularly in the complex terrain of bipolar disorder. It's like searching for a mirage in the desert – sometimes we find what we're looking for, and sometimes we find something else entirely. While the results of this study may be disappointing, it's important to remember that this research serves as a stepping stone in our quest for better treatments for bipolar disorder and anxiety. We must continue our journey, seeking out new and more effective approaches to help those who are struggling.

Date :
  1. Date Completed 2009-08-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19042026

DOI: Digital Object Identifier

10.1016/j.jad.2008.10.005

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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