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Efficacy of intracarotid propofol infusion and impact of cerebral blood flow alteration.
Author: FanY Y, LaoN, NieH, WangB R, XiongL Z, XuL X, ZhangH
Original Abstract of the Article :
BACKGROUND: Intracarotid propofol infusion was studied in canines as an experimental basis for application of propofol in the Wada test. METHODS: First, efficacy and side-effects of propofol anaesthesia were studied in eight mongrel dogs that received intracarotid and i.v. propofol infusions for 30...See full text at original site
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引用元:
https://doi.org/10.1093/bja/aen346
データ提供:米国国立医学図書館(NLM)
Propofol Infusion: A Journey Through the Brain
[Intracarotid propofol infusion] is a technique used to induce [anesthesia] in a specific region of the brain. It's like guiding a caravan through a narrow desert canyon – the anesthetic effect is focused on a specific area. This study explored the [efficacy and side effects] of [intracarotid propofol infusion] in [canines], which provide valuable insights into the potential use of [propofol] in the [Wada test]. It's like exploring a new path through the desert – understanding how the terrain affects the journey is crucial for success.
Finding the Right Dose for Effective Anesthesia
The study found that [intracarotid propofol infusion] required significantly less [propofol] to achieve [anesthesia] compared to [intravenous infusion]. It's like using less fuel to navigate a narrow canyon – a more efficient approach. They also discovered that [increasing cerebral blood flow] required a higher dose of [propofol], suggesting that [patients with increased cerebral blood flow] might need a higher dosage during the [Wada test].
Navigating the Wada Test
This study helps to understand the unique aspects of [intracarotid propofol infusion], a valuable tool for [neurological testing]. It's like having a guide map for navigating a complex desert landscape – understanding the terrain can help you avoid potential hazards.
Dr.Camel's Conclusion
Propofol is a powerful tool for navigating the complexities of the brain. This research illuminates the unique characteristics of [intracarotid propofol infusion], providing valuable insights for [neurological testing]. It's like having a compass for exploring the intricate pathways of the brain.
Date :
- Date Completed 2009-02-20
- Date Revised 2018-01-26
Further Info :
Related Literature
English
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