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Phase III randomized study: oral pilocarpine versus submandibular salivary gland transfer protocol for the management of radiation-induced xerostomia.
Author: BarnabyPam, BlackMartin, ButlerJames, GhoshSunita, HarrisJeffrey, HierMichael, JhaNaresh, KerrPaul, SeikalyHadi, SultanemKhalil, SutherlandDonna, WilliamsDavid
Original Abstract of the Article :
BACKGROUND: Xerostomia is a serious morbidity of radiation treatment in head and neck cancer. METHODS: We conducted a prospective phase III multicenter randomized study comparing submandibular salivary gland transfer (SGT) procedure with pilocarpine during and for 3 months after XRT. Salivary flow ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/hed.20961
データ提供:米国国立医学図書館(NLM)
Combatting Xerostomia: Finding Oasis in the Desert of Radiation-Induced Dry Mouth
Radiation therapy, a powerful weapon in the fight against cancer, can sometimes have unintended consequences. Xerostomia, or dry mouth, is a common side effect, leaving patients feeling like they are traversing a desert. This study, like a compassionate explorer seeking solutions, compares two treatment approaches for radiation-induced xerostomia: submandibular salivary gland transfer (SGT) and oral pilocarpine. The results, like a wellspring in the desert, show that SGT outperformed pilocarpine in improving salivary flow and overall quality of life.
Salivary Gland Transfer: A Potential Oasis for Xerostomia
This research, like a ray of hope in the desert, unveils the potential of SGT for combating xerostomia. The findings suggest that SGT, a more invasive procedure, can significantly improve salivary flow and overall quality of life compared to pilocarpine, a less invasive option. This information is crucial for patients and healthcare providers to weigh the potential benefits and risks of each treatment approach.
Navigating Dry Mouth: Seeking Relief in the Desert
This research, like a map guiding a traveler through a dry and barren landscape, provides valuable information for patients experiencing xerostomia. It highlights the potential of SGT as a treatment option, while also acknowledging the need for further research to fully understand its long-term effectiveness and to explore other potential interventions.
Dr. Camel's Conclusion
This study, like a camel caravan discovering a new oasis, unveils the potential of salivary gland transfer as a treatment for radiation-induced xerostomia. It highlights the importance of exploring different treatment options and making informed decisions about the best approach for individual patients.
Date :
- Date Completed 2009-05-21
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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