Perforating folliculitis, angioedema, hand-foot syndrome--multiple cutaneous side effects in a patient treated with sorafenib.

Author: SchneebergerAchim, TatzreiterGeorg, UdvardiAstrid, Volc-PlatzerBeatrix, WolberCarola

Paper Details 
Original Abstract of the Article :
A patient with clear cell renal cell carcinoma was treated with sorafenib, a multikinase inhibitor, which induced a variety of cutaneous side effects. In addition to xerosis, he developed angioedema (AE), hand-foot syndrome (HFS) and perforating folliculitis (PF). The latter three occurred in a dose...See full text at original site
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引用元:
https://doi.org/10.1111/j.1610-0387.2009.07017.x

データ提供:米国国立医学図書館(NLM)

Sorafenib: A Desert Oasis of Hope with Unexpected Side Effects

The field of oncology is a vast desert where researchers tirelessly seek new therapies to combat cancer. This study, much like a seasoned explorer navigating a challenging terrain, documents the experience of a patient treated with sorafenib, a multikinase inhibitor, for clear cell renal cell carcinoma. The research highlights the various cutaneous side effects experienced by the patient, including xerosis, angioedema (AE), hand-foot syndrome (HFS), and perforating folliculitis (PF). The authors describe the dose-dependent nature of these side effects, observing that AE, HFS, and PF appeared at different dose levels. The study aims to raise awareness of the potential for these side effects during sorafenib treatment, encouraging close monitoring of patients and dose adjustments as needed.

Unveiling the Side Effects of Sorafenib: Navigating the Desert of Treatment

This study reports a case of a patient experiencing a range of cutaneous side effects during treatment with sorafenib. The authors highlight the dose-dependent nature of these side effects, emphasizing the importance of careful monitoring and dose adjustments. The study's findings, like a map of unexpected terrain in the desert, provide valuable insights for healthcare professionals managing patients on sorafenib therapy.

Managing Cancer Treatment Side Effects: A Desert of Challenges and Solutions

The desert provides a powerful analogy for understanding the challenges of cancer treatment. Just as a traveler must adapt to the harsh conditions of a desert, patients undergoing cancer treatment must navigate a range of potential side effects. This study underscores the importance of a proactive approach to managing these side effects, working closely with healthcare professionals to optimize treatment and minimize discomfort. By understanding the potential side effects of therapies and actively addressing them, we can improve the quality of life for cancer patients during their treatment journey.

Dr. Camel's Conclusion

This research, like a guidebook through the desert of cancer treatment, highlights the importance of understanding the potential side effects of therapies. The study documents a case of a patient experiencing a range of cutaneous side effects during treatment with sorafenib, emphasizing the need for close monitoring and dose adjustments to manage these challenges. This work serves as a valuable resource for healthcare professionals, providing insights into the potential side effects of sorafenib and guiding them in providing optimal care for their patients.

Date :
  1. Date Completed 2009-09-04
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

19178612

DOI: Digital Object Identifier

10.1111/j.1610-0387.2009.07017.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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