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Impact of recent prior opioid use on rizatriptan efficacy. A post hoc pooled analysis.

Author: BigalMarcelo E, HoTony W, RodgersAnthony

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Recent prior opioid use was associated with lower triptan response.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Limited evidence suggests that, in individuals with migraine, prior use of opioids reduces responsiveness to treatment with subsequent acute migraine therapies. The evidence is more robust with regard to opioids as a risk factor for chronic migraine. OBJECTIVES: To explore whether recen...See full text at original site
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引用元：
https://doi.org/10.1111/j.1526-4610.2009.01346.x

データ提供：米国国立医学図書館（NLM）

Impact of Recent Prior Opioid Use on Rizatriptan Efficacy

The battle against [migraine] is a challenging one, and finding effective treatments is a top priority for many. This study examines the impact of recent opioid use on the efficacy of [rizatriptan], a commonly prescribed migraine medication. Researchers delved into the data from previous clinical trials to see if prior opioid use affected the effectiveness of rizatriptan. Their findings, like a desert windstorm, revealed a potentially problematic interaction.

Opioids and Migraine Treatments: A Complex Relationship

The study found a concerning trend: recent opioid use may significantly reduce the effectiveness of rizatriptan in treating migraines. This finding suggests a potential for reduced therapeutic response in patients who have used opioids recently.

Navigating the Desert of Migraine Relief

This research highlights the importance of careful consideration when using opioids for pain management, particularly for migraine. Patients with migraine who have recently used opioids may need to explore alternative treatment approaches to achieve effective relief.

Dr. Camel's Conclusion

This study sheds light on the complex relationship between opioids and migraine treatment. It suggests that prior opioid use may impact the efficacy of certain migraine medications, prompting a need for further investigation and alternative treatment strategies for individuals who have recently used opioids.
Date :
  1. Date Completed 2009-06-15
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

19222588

DOI: Digital Object Identifier

10.1111/j.1526-4610.2009.01346.x

Related Literature

Article Analysis
・Effective treatment of migraine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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