Safety of 17D derived yellow fever vaccines.

Author: DomingoCristina, NiedrigMatthias

Paper Details 
Original Abstract of the Article :
BACKGROUND: Yellow fever, a mosquito-borne viral haemorrhagic fever, is one of the most lethal viral diseases. At present, an efficient vaccine for prevention is available, but may cause serious adverse events. METHODS: The authors review the up-to-date knowledge for serious adverse events of the y...See full text at original site
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引用元:
https://doi.org/10.1517/14740330902808086

データ提供:米国国立医学図書館(NLM)

Yellow Fever Vaccine: A Vital Tool with Potential Side Effects

Yellow fever, a serious mosquito-borne disease, presents a significant public health threat. Fortunately, a vaccine offers protection, but it can also cause adverse events, making it essential to understand its risks. This study reviews the current knowledge on serious adverse events (YFSAE) associated with the yellow fever vaccine, including hypersensitivity reactions and neurotropic and viscerotropic syndromes. The authors highlight the importance of recognizing YFSAE, emphasizing that while rare, they must be prevented. They also call for further research to better understand the complex interplay between the virus and the host's immune response.

Understanding the Risks and Benefits of Yellow Fever Vaccination

The study reveals that YFSAE are linked to factors such as age and thymus disorders. However, many cases remain unexplained, suggesting that other factors might contribute to these post-vaccination reactions. This underscores the importance of careful risk assessment before vaccination and the need to continue research to identify and manage these potential side effects.

Protecting Public Health with Informed Vaccination Strategies

This study emphasizes the need for informed decision-making regarding vaccination. The authors advocate for restricting vaccination to individuals at a genuine risk of exposure to the wild-type yellow fever virus. This approach balances the benefits of vaccination with the potential risks associated with YFSAE.

Dr.Camel's Conclusion

Like navigating a desert with treacherous mirages, understanding the risks and benefits of the yellow fever vaccine is crucial. While the vaccine provides invaluable protection, it's essential to be aware of the potential for adverse events. By staying informed and consulting with healthcare professionals, we can make informed decisions to protect public health and ensure a safer journey through the desert of disease.

Date :
  1. Date Completed 2009-06-15
  2. Date Revised 2019-11-11
Further Info :

Pubmed ID

19309249

DOI: Digital Object Identifier

10.1517/14740330902808086

Related Literature

SNS
PICO Info
in preparation
Languages

English

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