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Systemic treatment in severe cases of recurrent aphthous stomatitis: an open trial.
Author: HirotaSilvio Kenji, MigliariDante Antonio, MimuraMaria Angela Martins, SanchesJosé Antonio, SugayaNorberto Nobuo
Original Abstract of the Article :
PURPOSE: This study aimed to evaluate the efficacy of the systemic drugs thalidomide, dapsone, colchicine, and pentoxifylline in the treatment of severe manifestations of RAS. METHODS: An open, 4-year clinical trial was carried out for 21 consecutive patients with severe RAS. Initially, patients we...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666466/
データ提供:米国国立医学図書館(NLM)
Systemic Treatment of Recurrent Aphthous Stomatitis: A Search for Relief
The world of [oral medicine] is a desert where [recurrent aphthous stomatitis (RAS)] can create discomfort and pain. This study, like a dedicated clinician seeking relief for their patients, explored the effectiveness of [systemic drugs] for [treating severe manifestations of RAS]. The researchers, using an [open clinical trial], aimed to [evaluate the efficacy of thalidomide, dapsone, colchicine, and pentoxifylline] in [managing RAS symptoms]. Their findings reveal [that thalidomide was the most effective and well-tolerated drug], leading to [complete remission] in a significant portion of patients. This study offers a beacon of hope for patients struggling with RAS, providing a potential path to symptom relief. The key takeaway is that [thalidomide may be an effective treatment option for severe RAS].
Finding Relief in the Desert of RAS
The study found that [thalidomide significantly reduced RAS symptoms] and led to [complete remission] in many patients. This is like a camel finding a cool spring in the desert, bringing a much-needed reprieve from the heat and dryness. The findings also indicate that [dapsone, colchicine, and pentoxifylline] provided [benefit] for some patients, offering additional options for [managing RAS symptoms].
Navigating the Desert of Oral Discomfort
This research offers a valuable resource for clinicians treating patients with [RAS]. It's like finding a new route through a challenging desert, providing a more effective and comfortable journey. The study's findings underscore the importance of [considering systemic therapies] for [severe RAS cases] and the potential for [thalidomide] to play a significant role in [managing this condition].
Dr.Camel's Conclusion
This study reminds us that even in the challenging desert of RAS, there may be hidden oases of relief waiting to be discovered. Thalidomide offers a promising path to symptom management for many patients, providing a more comfortable journey through this difficult terrain.
Date :
- Date Completed 2010-02-09
- Date Revised 2022-06-29
Further Info :
Related Literature
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