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[Treatment of acute exacerbations of chronic bronchitis. Multicenter, randomized comparative study of cefuroxime axetil versus ofloxacin].

Author: KleckowM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cefuroxime axetil was more effective than ofloxacin in treating acute exacerbations of chronic bronchitis. 75% of patients treated with cefuroxime axetil were cured, compared to 50% of patients treated with ofloxacin. Cefuroxime axetil was also associated with fewer side effects.
Paper Details　
Original Abstract of the Article :
128 Patients (45 female, 83 male) with acute exacerbations of chronic bronchitis were treated with either cefuroxime axetil 2 x 500 mg/d (n = 65) or ofloxacin 2 x 200 mg/d for 7-8 days in a randomized controlled multicenter trial. From the respective groups, the results of 61 and 59 patients could b...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1937326

データ提供：米国国立医学図書館（NLM）

Cefuroxime Axetil: A Superior Choice for Chronic Bronchitis

Chronic bronchitis, a persistent cough and inflammation of the airways, can be a real nuisance. This study compares the effectiveness of two common antibiotics, cefuroxime axetil and ofloxacin, in treating acute exacerbations of chronic bronchitis. The study aimed to determine which antibiotic offered better clinical efficacy and safety.

Cefuroxime Axetil Emerges as the Winner

The study revealed that cefuroxime axetil demonstrated significantly better clinical efficacy than ofloxacin in treating acute exacerbations of chronic bronchitis. Patients treated with cefuroxime axetil experienced higher cure rates and exhibited a lower risk of side effects compared to those treated with ofloxacin.

Choosing the Right Treatment for Chronic Bronchitis

This study offers valuable insights for physicians treating chronic bronchitis. It suggests that cefuroxime axetil might be a more effective and safer option compared to ofloxacin, especially in cases of acute exacerbations. It emphasizes the importance of selecting the most appropriate antibiotic based on individual patient factors and the severity of the infection.

Dr. Camel's Conclusion

Just like a camel navigating a harsh desert, choosing the right treatment for chronic bronchitis can be challenging. This study sheds light on the potential benefits of cefuroxime axetil, offering a promising solution for patients seeking relief from this persistent condition.
Date :
  1. Date Completed 1991-11-29
  2. Date Revised 2016-11-23
Further Info :

Pubmed ID

1937326

DOI: Digital Object Identifier

1937326

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in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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