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Comparison of oral falecalcitriol and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism: a randomized, crossover trial.
Author: ItoH, KinugasaE, OgataH, ShishidoK, TaguchiS, TakahashiJ, TakahashiK, YamamotoM
Original Abstract of the Article :
BACKGROUND: Falecalcitriol is a novel vitamin D analog, which has a greater potential to suppress parathyroid hormone (PTH) and a longer half-life. There are few studies to compare clinical effects of oral falecalcitriol treatment with those of intravenous calcitriol treatment. METHODS: Twenty-one ...See full text at original site
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引用元:
https://doi.org/10.5414/cnp71660
データ提供:米国国立医学図書館(NLM)
Comparing Oral Falecalcitriol and Intravenous Calcitriol for Secondary Hyperparathyroidism in Hemodialysis Patients
This research dives into the world of vitamin D analogs, exploring their potential for managing secondary hyperparathyroidism (SHPT) in folks on hemodialysis. It's like a desert oasis for these patients, desperately seeking relief from the parched landscape of elevated parathyroid hormone (PTH). The study used a crossover design, switching patients between oral falecalcitriol and intravenous calcitriol treatments. The authors found that both forms of vitamin D effectively lowered PTH levels, offering a ray of hope for patients with SHPT.
Both Falecalcitriol and Calcitriol Show Promise in PTH Reduction
The study found that both oral falecalcitriol and intravenous calcitriol reduced PTH levels similarly. It's like discovering two equally effective watering holes in the vast desert of SHPT treatment options. The results highlight that these options, while different in delivery methods, can contribute to a healthy balance within the body.
The Benefits of Vitamin D Analogs for Hemodialysis Patients
This research provides a vital clue to the puzzle of SHPT management in hemodialysis patients. It indicates that both falecalcitriol and calcitriol can be used to help stabilize calcium and phosphate levels, which are crucial for healthy bones and overall well-being. It's like finding two valuable tools for navigating the treacherous sands of kidney disease.
Dr. Camel's Conclusion
This research demonstrates that both oral falecalcitriol and intravenous calcitriol have the potential to help patients with SHPT on hemodialysis. It's a double dose of good news for these individuals. The findings offer a promising pathway for better managing SHPT, which can often be a challenging condition to treat. Further research is still needed to fully understand the long-term implications of these treatment options.
Date :
- Date Completed 2009-07-23
- Date Revised 2019-06-08
Further Info :
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