[Severe bronchial spasm crises induced by topical administration of eyedrops with timolol base, a non-selective beta blocking agent].

Author: AiolfiS, ConfalonieriM, Della PortaR, GandolaL, GhioL, MauriF, PatriniG, ScartabellatiA

Paper Details 
Original Abstract of the Article :
Since their introduction in clinical practice beta-blocker drugs are known to be able to induce bronchospasm. However, this adverse effect may develop only in subjects with asthma, chronic bronchitis and/or airways hyper-reactivity. Although this potentially adverse effect of beta-blockers on the ai...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1947406

データ提供:米国国立医学図書館(NLM)

Timolol Eyedrops: A Potential Trigger for Bronchospasm

Beta-blockers, a class of drugs commonly used to treat high blood pressure and other cardiovascular conditions, are known to have the potential to induce bronchospasm in individuals with pre-existing respiratory conditions like asthma, chronic bronchitis, or airways hyper-reactivity. This study investigates a case of severe bronchospasm episodes, with respiratory failure, following the administration of a timolol ophthalmic solution to a patient.

A Cautionary Tale: Timolol Eyedrops and Bronchospasm

The study reports a case of severe bronchospasm in a patient who received timolol eyedrops. This case highlights the potential for timolol, even when administered topically, to trigger bronchospasm in susceptible individuals. This finding emphasizes the importance of careful patient selection and the need to be aware of the potential risks associated with using timolol eyedrops, especially in patients with a history of respiratory problems.

Important Considerations for Patients and Healthcare Providers

This case report serves as a reminder of the potential for beta-blockers, including topical formulations like timolol eyedrops, to induce bronchospasm in susceptible individuals. Healthcare providers should be aware of this risk and exercise caution when prescribing timolol eyedrops, especially for patients with a history of respiratory conditions.

Dr. Camel's Conclusion

Imagine a vast desert where the air can shift from calm to turbulent in an instant. This study, like a camel weathering a sandstorm, warns of the potential for timolol eyedrops to trigger bronchospasm in susceptible individuals. This case highlights the importance of being aware of the potential risks and exercising caution when using beta-blockers, especially in those with pre-existing respiratory conditions.

Date :
  1. Date Completed 1991-12-17
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1947406

DOI: Digital Object Identifier

1947406

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PICO Info
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Languages

Italian

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