Response of vitiligo to once- vs. twice-daily topical tacrolimus: a controlled prospective, randomized, observer-blinded trial.

Author: Breier-MalyJ, HoenigsmannH, KittlerH, KonschitzkyR, RadakovicS, SatorP, TanewA

Paper Details 
Original Abstract of the Article :
BACKGROUND: A few studies on the treatment of vitiligo with topical tacrolimus have been published and showed promising results. However, most of these trials were uncontrolled. OBJECTIVE: This study aims to assess the response of vitiligo to once- or twice-daily treatment with 0.1% tacrolimus in a...See full text at original site
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引用元:
https://doi.org/10.1111/j.1468-3083.2009.03138.x

データ提供:米国国立医学図書館(NLM)

Topical Tacrolimus for Vitiligo: A Randomized Trial

Vitiligo, a skin condition characterized by depigmentation, can significantly impact a person's appearance and self-esteem. This study investigates the efficacy of topical tacrolimus, an immunosuppressant medication, in treating vitiligo. The researchers designed a controlled, randomized, and observer-blinded trial comparing the effects of once-daily and twice-daily tacrolimus application. The study reveals that twice-daily tacrolimus is more effective than once-daily application, particularly for facial vitiligo. The findings underscore the importance of selecting the appropriate treatment regimen based on the location and severity of vitiligo.

Tacrolimus for Vitiligo: A Potential Treatment

The study findings suggest that topical tacrolimus can be an effective treatment option for vitiligo, especially for facial lesions. The researchers found that twice-daily application resulted in significant repigmentation, providing valuable insights for clinicians managing this condition. The study emphasizes the need for individualized treatment strategies based on the specific characteristics of vitiligo.

Managing Vitiligo: A Journey of Hope

This study offers hope to individuals with vitiligo, suggesting that topical tacrolimus can be a valuable tool for managing this condition. The findings highlight the importance of seeking expert advice and following a treatment regimen tailored to individual needs. Like a desert traveler seeking a source of water, individuals with vitiligo can find hope and relief through appropriate treatment and ongoing management.

Dr. Camel's Conclusion

The desert of vitiligo can be a challenging landscape, leaving individuals with a feeling of isolation and self-consciousness. This study offers a ray of hope, revealing the potential of topical tacrolimus to restore pigmentation and improve quality of life. It reminds us that even in the face of adversity, there are treatment options available, offering a path toward healing and acceptance.

Date :
  1. Date Completed 2009-10-13
  2. Date Revised 2021-05-03
Further Info :

Pubmed ID

19496898

DOI: Digital Object Identifier

10.1111/j.1468-3083.2009.03138.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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