Effects of escitalopram on anxiety and respiratory responses to carbon dioxide inhalation in subjects at high risk for panic disorder: a placebo-controlled, crossover study.

Author: CoryellWilliam, RickelsHeather

Paper Details 
Original Abstract of the Article :
Individuals with panic disorder and those at high risk for panic disorder due to a positive family history seem to have elevated sensitivities to the panicogenic effects of carbon dioxide (CO2) inhalation as well as abnormal ventilatory responses to low doses of CO2 exposure. Many reports have descr...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19512981

データ提供:米国国立医学図書館(NLM)

Exploring the Link Between Anxiety and Carbon Dioxide Sensitivity in Panic Disorder

Anxiety disorders, such as [panic disorder], can significantly impact individuals' lives. This study investigates the relationship between [anxiety], [respiratory responses], and [carbon dioxide (CO2) inhalation] in individuals at high risk for panic disorder. The authors conducted a [placebo-controlled, crossover study], evaluating the effects of [escitalopram], a common antidepressant, on [anxiety] and [respiratory responses] to CO2 inhalation. The study's findings contribute to our understanding of the underlying mechanisms of panic disorder and offer insights into potential treatment strategies.

Escitalopram's Potential to Mitigate Panic-Inducing Effects of CO2 Inhalation

The study observed that individuals with a [positive family history] of panic disorder, much like camels navigating treacherous sand dunes, exhibit heightened sensitivity to the panicogenic effects of CO2 inhalation. Escitalopram demonstrated a potential to reduce [anxiety responses] to CO2 inhalation in these individuals, suggesting a promising therapeutic approach for managing panic-inducing symptoms. The study's findings, like a refreshing oasis in a vast desert, offer hope for individuals struggling with panic disorder.

Navigating the Complexities of Panic Disorder: Understanding CO2 Sensitivity and Treatment Options

This study, much like a desert expedition, provides a valuable glimpse into the complex interplay between [anxiety], [respiratory responses], and [carbon dioxide] in panic disorder. The findings highlight the potential of [escitalopram] to mitigate the panicogenic effects of CO2 inhalation, offering hope for individuals at high risk for developing panic disorder. However, further research is necessary to fully understand the mechanisms underlying these observations and to develop effective treatment strategies.

Dr. Camel's Conclusion

This study, much like a desert expedition, provides a valuable glimpse into the complex interplay between anxiety, respiratory responses, and carbon dioxide in panic disorder. The findings highlight the potential of escitalopram to mitigate the panicogenic effects of CO2 inhalation, offering hope for individuals at high risk for developing panic disorder. However, further research is necessary to fully understand the mechanisms underlying these observations and to develop effective treatment strategies.

Date :
  1. Date Completed 2009-08-18
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

19512981

DOI: Digital Object Identifier

00004714-200904000-00012

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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