Screening pharmaceuticals for possible carcinogenic effects: initial positive results for drugs not previously screened.

Author: ChanJames, FriedmanGary D, HabelLaurel A, QuesenberryCharles P, UdaltsovaNatalia

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To screen commonly used prescription drugs for possible carcinogenic effects. METHODS: In a large health care program we identified 105 commonly used drugs, not previously screened. Recipients were followed for up to 12½ years for incident cancer. Nested case-control analyses of 55 cance...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/19582585

データ提供:米国国立医学図書館(NLM)

Drug Safety: A Journey Through the Desert of Potential Carcinogenic Effects

In the vast desert of medical knowledge, ensuring the safety of pharmaceuticals is a constant quest. This study, like a team of intrepid explorers venturing into uncharted territories, embarks on a journey to screen commonly used prescription drugs for potential carcinogenic effects. The researchers, with the meticulousness of archaeologists uncovering ancient artifacts, meticulously analyzed data from a large healthcare program, following patients for up to 12.5 years to identify any associations between drug use and incident cancers.

The researchers, like detectives piecing together a complex puzzle, investigated associations between 105 commonly used drugs and 55 cancer sites. They employed nested case-control analyses, carefully comparing cases of cancer with matched controls to identify potential risk factors. Their findings reveal a complex landscape of potential drug-cancer associations, emphasizing the importance of ongoing vigilance in monitoring drug safety.

The Shadows of Cancer: Uncovering Potential Risks

The study, like a warning beacon in a desert storm, identifies several drugs that may be associated with increased cancer risk. While these findings are preliminary and require further investigation, they highlight the importance of ongoing research and surveillance to ensure the safety of pharmaceuticals. The authors, like wise guides urging caution, recommend further studies to confirm or refute these potential associations.

Navigating the Desert of Drug Safety: A Call for Continued Vigilance

This study serves as a reminder that even seemingly safe drugs can have unforeseen consequences. It underscores the importance of ongoing research, surveillance, and vigilance in ensuring the safety of pharmaceuticals. As we continue to explore the vast desert of medical knowledge, it's crucial to remain vigilant and adapt our practices to minimize potential risks.

Dr. Camel's Conclusion

This study reminds us that the desert of medical knowledge is vast and often unforgiving. While pharmaceuticals offer incredible benefits, it's crucial to remain vigilant about potential side effects. Further research and ongoing surveillance are essential for ensuring the safety of the medicines we rely on.

Date :
  1. Date Completed 2011-06-21
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

19582585

DOI: Digital Object Identifier

NIHMS234636

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.