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Multiple antibiotic sensitivity in a pediatric population.

Author: KamadaM M, LeungD Y, TwarogF

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Multiple antibiotic sensitivity (MAS) is common in children. Beta-lactam and sulfonamide antibiotics were the most frequent causes of reactions. Skin tests were positive in 26% of MAS patients, indicating IgE-mediated reactions.
Paper Details　
Original Abstract of the Article :
Multiple antibiotic sensitivity (MAS), a common but complex clinical problem, has not been reviewed in the pediatric population. We evaluated 120 children with a history of MAS. The offending antibiotics were beta lactam (186 adverse reactions), sulfonamide (86 adverse reactions), macrolide (32 adve...See full text at original site
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引用元：
https://doi.org/10.2500/108854191778879124

データ提供：米国国立医学図書館（NLM）

Multiple Antibiotic Sensitivity in Children: A Complex Challenge

Multiple antibiotic sensitivity (MAS), a common but complex clinical problem, is explored in this study, focusing on the pediatric population. The authors evaluated 120 children with a history of MAS, identifying the most prevalent offending antibiotics and the associated reactions. The study highlights the importance of recognizing the true allergic nature of MAS in children, emphasizing the need for careful evaluation and appropriate management strategies.

Understanding the Nature of MAS

The study clarifies the often-misunderstood nature of MAS in children, emphasizing that true IgE-mediated reactions are the primary cause of this condition. This finding underscores the importance of accurate allergy testing to determine the specific antibiotic sensitivities and guide appropriate treatment decisions.

Managing Antibiotic Sensitivity in Children

The study emphasizes the importance of individualized antibiotic management in children with MAS, prioritizing the use of safe and effective alternatives to minimize the risk of adverse reactions. This research provides valuable insights for healthcare providers to ensure the safe and appropriate use of antibiotics in this vulnerable population.

Dr. Camel's Conclusion

Navigating the world of antibiotics for children with MAS is like navigating a shifting desert landscape. This research provides a valuable compass for healthcare professionals, guiding them in understanding the complexities of MAS and ensuring the safe and effective use of antibiotics in this delicate terrain.

Date :
  1. Date Completed 1992-01-08
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

1959773

DOI: Digital Object Identifier

10.2500/108854191778879124

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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