Short-term cyproheptadine therapy in underweight children: effects on growth and serum insulin-like growth factor-I.

Author: ChoubtumLulin, MahachoklertwattanaPat, PoomthavornPreamrudee, SriphrapradangArporn, WanasuwankulSanthira

Paper Details 
Original Abstract of the Article :
Cyproheptadine, an appetite stimulant, has been used in poor-appetite underweight children. Its beneficial effects on enhancing growth rate have been demonstrated. In contrast, an adverse effect on blunting growth hormone (GH) secretion has also been reported. To date, however, its effect on insulin...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1515/jpem.2009.22.5.425

データ提供:米国国立医学図書館(NLM)

Cyproheptadine and Growth: A Tale of Two Hormones

Cyproheptadine, an appetite stimulant, has been used to address growth concerns in underweight children. This study investigates the effects of cyproheptadine on growth and serum insulin-like growth factor-I (IGF-I), a key growth hormone-mediated factor. The researchers, like scientists studying the delicate balance of hormones and growth, meticulously analyze the impact of cyproheptadine on these important factors.

Exploring the Growth Oasis: Cyproheptadine's Impact on Growth and IGF-I

The study reveals that while cyproheptadine may enhance growth rate, its effects on IGF-I levels remain inconclusive. This finding suggests that cyproheptadine's impact on growth may be complex and warrant further investigation to understand its full effects on growth hormone and its downstream mediators. The researchers emphasize the importance of continued research to determine the long-term effects of cyproheptadine on growth and development.

Navigating the Growth Desert: Choosing the Right Approach for Underweight Children

This research highlights the importance of a comprehensive approach to addressing growth concerns in underweight children. The study's findings encourage clinicians to carefully consider the potential benefits and risks of cyproheptadine therapy, while exploring other strategies for promoting healthy growth and development. By embracing a personalized approach to treatment and collaborating with families to address underlying factors contributing to underweight, we can create a more effective and holistic approach to supporting the growth and well-being of children.

Dr. Camel's Conclusion

This study delves into the complex interplay between cyproheptadine, growth hormone, and IGF-I, providing valuable insights into the potential benefits and risks of this medication for underweight children. The research underscores the need for further investigation to fully understand the long-term effects of cyproheptadine on growth and development. By continuing to explore the factors influencing growth and developing more effective treatment strategies, we can create a brighter future for all children, ensuring they reach their full potential.

Date :
  1. Date Completed 2009-09-09
  2. Date Revised 2019-09-07
Further Info :

Pubmed ID

19618661

DOI: Digital Object Identifier

10.1515/jpem.2009.22.5.425

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.