Paper Details 
Original Abstract of the Article :
The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria. Cetirizine markedly reduced...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1969202

データ提供:米国国立医学図書館(NLM)

Cetirizine: A Desert Oasis for Chronic Urticaria

Chronic urticaria, a condition characterized by persistent hives, can be a frustrating and uncomfortable experience, like navigating a desert plagued by constant stinging insects. This study investigates the effectiveness of cetirizine, an antihistamine, in treating chronic urticaria by examining its impact on cutaneous reactions to various stimuli, including platelet activating factor (PAF), kallikrein, histamine, and the patient's own serum.

Cetirizine: A Powerful Ally in the Fight Against Chronic Urticaria

The study demonstrates that cetirizine effectively reduces both the immediate and delayed weal and flare reactions induced by these stimuli, suggesting its potential as a valuable therapeutic agent for managing chronic urticaria. The findings provide a clear rationale for considering cetirizine as a first-line treatment option for this challenging condition.

Finding Relief from the Desert of Chronic Urticaria

The study provides a beacon of hope for individuals struggling with chronic urticaria, suggesting that a simple treatment like cetirizine can effectively alleviate symptoms. This research highlights the importance of understanding the underlying mechanisms of chronic urticaria and the potential of antihistamines in managing this condition.

Dr.Camel's Conclusion

This study demonstrates the effectiveness of cetirizine in reducing cutaneous reactions to various stimuli in patients with chronic urticaria. This antihistamine shows promise as a valuable therapeutic agent for managing this challenging condition, offering a potential oasis of relief for individuals struggling with persistent hives. The research encourages further exploration of cetirizine's role in chronic urticaria management, potentially leading to improved treatment strategies and a better quality of life for affected individuals.

Date :
  1. Date Completed 1990-04-26
  2. Date Revised 2019-11-27
Further Info :

Pubmed ID

1969202

DOI: Digital Object Identifier

102340/0001555570151153

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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