Paper Details 
Original Abstract of the Article :
Epidemiologic studies indicate that nearly 60% of schizophrenia (SZ) patients treated with conventional antipsychotic drugs develop extrapyramidal side effects (EPS) such as parkinsonism and tardive dyskinesia. Although the prevalence of EPS has decreased due to the newer antipsychotics, EPS continu...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19692133

データ提供:米国国立医学図書館(NLM)

Handwriting: A New Oasis in the Desert of Drug-Induced Motor Side Effects

The [schizophrenia] landscape is often characterized by a search for effective treatments that minimize side effects. This study explores the potential of handwriting movement analysis as a tool to monitor drug-induced motor side effects in schizophrenia patients treated with risperidone. The authors aimed to assess the sensitivity of handwriting kinematics in detecting extrapyramidal side effects (EPS) and their association with risperidone dose.

A Telltale Trail: Handwriting Movements Reveal EPS

The research reveals that risperidone-treated participants exhibited significantly more dysfluent handwriting movements than either healthy or untreated schizophrenia participants. Handwriting dysfluency during sentence writing increased with risperidone dose. This finding suggests that handwriting movement analysis may be a sensitive tool for detecting EPS in schizophrenia patients, offering a valuable objective measure to complement traditional clinical assessments.

Navigating the Sands of Medication Monitoring

This study highlights the importance of comprehensive medication monitoring in schizophrenia patients. It emphasizes the need to consider both subjective and objective measures of EPS, such as handwriting analysis. The authors suggest that incorporating handwriting analysis into routine clinical practice could improve detection of EPS and facilitate adjustments in medication regimens, leading to better treatment outcomes.

Dr. Camel's Conclusion

In the vast desert of schizophrenia treatment, we seek to find the most effective and well-tolerated paths. This study suggests that handwriting analysis may be a valuable tool for navigating the shifting sands of drug-induced motor side effects. Like a camel leaving a trail in the sand, our handwriting movements can provide insights into our neurological health. By utilizing this unique form of assessment, we can better monitor the effects of medications and strive to optimize treatment for those living with schizophrenia.

Date :
  1. Date Completed 2010-01-08
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

19692133

DOI: Digital Object Identifier

NIHMS139909

Related Literature

SNS
PICO Info
in preparation
Languages

English

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