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Handwriting movement analyses for monitoring drug-induced motor side effects in schizophrenia patients treated with risperidone.
Author: CaligiuriMichael P, DeanCharles E, LohrJames, NiculescuAlexander B, TeulingsHans-Leo
Original Abstract of the Article :
Epidemiologic studies indicate that nearly 60% of schizophrenia (SZ) patients treated with conventional antipsychotic drugs develop extrapyramidal side effects (EPS) such as parkinsonism and tardive dyskinesia. Although the prevalence of EPS has decreased due to the newer antipsychotics, EPS continu...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/19692133
データ提供:米国国立医学図書館(NLM)
Handwriting: A New Oasis in the Desert of Drug-Induced Motor Side Effects
The [schizophrenia] landscape is often characterized by a search for effective treatments that minimize side effects. This study explores the potential of handwriting movement analysis as a tool to monitor drug-induced motor side effects in schizophrenia patients treated with risperidone. The authors aimed to assess the sensitivity of handwriting kinematics in detecting extrapyramidal side effects (EPS) and their association with risperidone dose.
A Telltale Trail: Handwriting Movements Reveal EPS
The research reveals that risperidone-treated participants exhibited significantly more dysfluent handwriting movements than either healthy or untreated schizophrenia participants. Handwriting dysfluency during sentence writing increased with risperidone dose. This finding suggests that handwriting movement analysis may be a sensitive tool for detecting EPS in schizophrenia patients, offering a valuable objective measure to complement traditional clinical assessments.
Navigating the Sands of Medication Monitoring
This study highlights the importance of comprehensive medication monitoring in schizophrenia patients. It emphasizes the need to consider both subjective and objective measures of EPS, such as handwriting analysis. The authors suggest that incorporating handwriting analysis into routine clinical practice could improve detection of EPS and facilitate adjustments in medication regimens, leading to better treatment outcomes.
Dr. Camel's Conclusion
In the vast desert of schizophrenia treatment, we seek to find the most effective and well-tolerated paths. This study suggests that handwriting analysis may be a valuable tool for navigating the shifting sands of drug-induced motor side effects. Like a camel leaving a trail in the sand, our handwriting movements can provide insights into our neurological health. By utilizing this unique form of assessment, we can better monitor the effects of medications and strive to optimize treatment for those living with schizophrenia.
Date :
- Date Completed 2010-01-08
- Date Revised 2022-04-10
Further Info :
Related Literature
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