Paper Details

  1. Home
  2. Paper Details

Current trends in the treatment of hepatic encephalopathy.

Author: Al SibaeMohamad Rasm, McGuireBrendan M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Hepatic encephalopathy (HE) is a common problem in people with liver disease. While a clear cause is still unknown, high ammonia levels in the blood and brain are key. Treatment focuses on early detection and addressing things that worsen HE, such as infections. Lactulose and lactitol are effective treatments, but can cause digestive issues. Neomycin, metronidazole, and rifaximin are other options, with rifaximin having fewer side effects. New treatments being studied include nitazoxanide, MARS, L-ornithine phenylacetate, sodium benzoate/phenylacetate, and Kremezin.
Paper Details　
Original Abstract of the Article :
Hepatic encephalopathy (HE) is a common reversible neuropsychiatric syndrome associated with chronic and acute liver dysfunction and significant morbidity and mortality. Although a clear pathogenesis is yet to be determined, elevated ammonia in the serum and central nervous system are the mainstay f...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724191/

データ提供：米国国立医学図書館（NLM）

Hepatic Encephalopathy: Navigating the Desert of Liver Dysfunction

The [liver] is a vital organ, and when it's struggling, it can impact the entire body. This research delves into the complexities of [hepatic encephalopathy (HE)], a neuropsychiatric syndrome associated with liver dysfunction. The authors provide an overview of the current understanding of HE, including its causes, mechanisms, and treatment options.

Finding the Right Path: Managing Hepatic Encephalopathy

This research highlights the importance of early diagnosis and prompt treatment of HE, aiming to minimize its potentially serious consequences. It's like navigating a desert, where finding the right path can mean the difference between survival and peril. The study also discusses the efficacy of various treatment strategies, including lactulose, lactitol, neomycin, metronidazole, and rifaximin, and explores the potential benefits of newer therapies like nitazoxanide, the molecular adsorbent recirculating system (MARS), and L-ornithine phenylacetate.

A Journey Through Liver Dysfunction: Staying Healthy

This research provides valuable insights for those living with chronic liver disease and experiencing HE. It emphasizes the importance of adhering to treatment plans, managing precipitating factors, and seeking prompt medical attention if symptoms worsen.

Dr. Camel's Conclusion

This research sheds light on the complexities of HE, highlighting the importance of early diagnosis, prompt treatment, and ongoing research to improve the lives of those affected by this challenging condition.

Date :
  1. Date Completed 2011-07-14
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

19707277

DOI: Digital Object Identifier

PMC2724191

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.