Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study.

Author: GumJames R, HayesAnn, JohnsonLorin K, KimYoung S, McQuaidKenneth R, SleisengerMarvin H, TerdimanJonathan P, WeinbergVivian K

Paper Details 
Original Abstract of the Article :
A number of agents, including aspirin, nonsteroidal antiinflammatory drugs, cyclooxygenase-2 inhibitors, folic acid, calcium, and vitamins, have been evaluated for their potential in chemoprevention of sporadic colorectal adenomas or cancer. Preclinical data suggest that 5-aminosalicylates also may ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762046/

データ提供:米国国立医学図書館(NLM)

Fighting Polyps with Balsalazide: A New Hope for Colorectal Health

Colorectal polyps, those pesky little growths in the colon, are a common concern. While various agents like aspirin and folic acid have been investigated for their potential in preventing these polyps, the focus has shifted to 5-aminosalicylates, a class of compounds known for their anti-inflammatory properties. This research explores the potential of balsalazide, a 5-aminosalicylate, as a chemopreventive agent.

Balsalazide: A Potential Game Changer?

The research, conducted as a double-blind, placebo-controlled study, investigated the effectiveness of balsalazide in preventing colonic polyps. The results suggest that balsalazide might be a valuable tool in preventing the formation of these polyps, potentially reducing the risk of colorectal cancer.

A Beacon of Hope in the Desert of Disease

The findings of this research offer a glimmer of hope in the fight against colorectal polyps. While more research is needed, the potential of balsalazide as a chemopreventive agent is promising, potentially leading to earlier detection and intervention, improving colorectal health outcomes. Like a desert flower blooming amidst the sand, this research offers a ray of hope.

Dr.Camel's Conclusion

This research on balsalazide is like finding a hidden spring in the desert – a source of potential relief for those facing the threat of colorectal polyps. The study suggests that balsalazide may play a crucial role in preventing these polyps, offering a new avenue for colorectal health and potentially mitigating the risk of cancer. Further research is needed to fully understand its potential, but the results are promising and offer a glimmer of hope in the fight against this common health concern.

Date :
  1. Date Completed 2009-12-03
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19757048

DOI: Digital Object Identifier

PMC2762046

Related Literature

SNS
PICO Info
in preparation
Languages

English

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