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Maintaining high hemoglobin levels improved the left ventricular mass index and quality of life scores in pre-dialysis Japanese chronic kidney disease patients.

Author: AkaishiMakoto, AkibaTakashi, AkizawaTadao, AonumaKazutaka, FukuharaShunichi, GejyoFumitake, HadaYoshiyuki, HirakataHideki, HiroeMichiaki, IinoYasuhiko, InagumaDaijo, MoritaSatoshi, NishiShinichi, SaitoAkira, SuzukiMakoto, SuzukiMasashi, TsubakiharaYoshiharu, WatanabeYuzou

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Targeting a higher hemoglobin (Hb) around 12 g/dl was more beneficial than targeting conventional Hb in terms of reduction of left ventricular mass index (LVMI) and quality of life (QOL) in pre-dialysis Japanese CKD patients.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Anemia is common among patients with chronic kidney disease (CKD). The introduction of erythropoietin treatment has changed anemia management, but the therapeutic hemoglobin (Hb) target is still under debate, and clinical evidence for its effect on cardiac functions and QOL is sparse. M...See full text at original site
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引用元：
https://doi.org/10.1007/s10157-009-0212-4

データ提供：米国国立医学図書館（NLM）

Hemoglobin Levels: A Key to Improved Cardiac Function and Quality of Life in CKD Patients

Anemia is a common complication of chronic kidney disease (CKD) and can significantly impact cardiac function and quality of life. This study investigates the effects of maintaining high hemoglobin (Hb) levels in pre-dialysis CKD patients. Researchers compared two Hb target levels—one higher (12-13 g/dl) and one conventional—and assessed their impact on left ventricular mass index (LVMI) and quality of life scores.

High Hemoglobin: A Positive Impact on Cardiac Health

The study found that maintaining a higher Hb level through erythropoietin treatment led to a significant decrease in LVMI and improvement in quality of life scores. These findings underscore the importance of managing anemia effectively in pre-dialysis CKD patients.

Managing Anemia: A Vital Component of CKD Care

This study emphasizes the importance of actively managing anemia in CKD patients. Maintaining a higher Hb level, within a safe range, can have a positive impact on both cardiac function and quality of life. This highlights the need for personalized treatment strategies that address the individual needs of each patient.

Dr.Camel's Conclusion

This study provides valuable evidence for the importance of maintaining high Hb levels in pre-dialysis CKD patients. The findings highlight the potential benefits of aggressive anemia management in improving cardiac function and quality of life. As a researcher, I am impressed by the dedication of healthcare professionals in seeking the best possible care for patients with CKD. Just as a camel adapts to the arid desert environment, we must continually adapt our approach to managing chronic diseases, ensuring that patients receive optimal care.
Date :
  1. Date Completed 2010-05-13
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

19763743

DOI: Digital Object Identifier

10.1007/s10157-009-0212-4

SNS
PICO Info
in preparation
Languages

English

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