Transient electrocardiographic changes suggesting myocardial ischaemia in newborn infants following tocolysis with beta-sympathomimetics.

Author: AgnettiA, De LucaF, Di PasqualeG, GemelliM, LeonardiR, MamiC, ManganaroR, RandoF

Paper Details 
Original Abstract of the Article :
Serial electrocardiograms (ECGs) were studied prospectively in 80 apparently healthy newborn infants; 30 infants exposed in utero to prolonged tocolytic therapy (21 to ritodrine and 9 to isoxsuprine) and 50 infants non-exposed in utero to drugs (control group) matched for gestational age, Apgar scor...See full text at original site
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引用元:
https://doi.org/10.1007/BF01959533

データ提供:米国国立医学図書館(NLM)

Tocolysis and Fetal Heart: Navigating the Risks of Beta-Sympathomimetics

The field of [obstetrics] is constantly seeking to balance the benefits and risks of [tocolysis], a practice used to delay premature labor. This prospective study investigated the potential impact of prolonged [beta-sympathomimetic] tocolysis on the fetal myocardium, using [electrocardiograms (ECGs)] to assess for signs of [myocardial ischemia]. The researchers observed that a significant proportion of infants exposed to prolonged tocolysis exhibited ECG changes suggestive of myocardial ischemia, raising concerns about potential cardiac side effects.

Tocolysis: A Balancing Act in Pregnancy

The study suggests that prolonged tocolysis with beta-sympathomimetics may carry a risk of fetal myocardial ischemia. The findings emphasize the need for careful consideration of the potential risks and benefits of tocolysis, particularly in cases of prolonged use. The research underscores the importance of monitoring fetal heart rate and other vital signs during tocolysis to detect any potential complications.

Making Informed Decisions During Pregnancy

For pregnant women facing premature labor, it’s essential to have open communication with healthcare providers about the potential risks and benefits of tocolysis. The study’s findings highlight the importance of weighing the benefits of delaying labor against the potential risks of tocolysis, particularly in cases of prolonged use. Close monitoring of fetal health during tocolysis is crucial to ensure a safe and healthy outcome for both mother and baby.

Dr. Camel's Conclusion

This study reminds us that even in the seemingly fertile landscape of pregnancy, there are hidden dangers that require careful navigation. Tocolysis, while a valuable tool for managing premature labor, can have unexpected consequences, particularly when used for extended periods. The research emphasizes the importance of careful monitoring and a balanced approach to tocolysis, ensuring that we navigate the challenges of pregnancy with both hope and caution.

Date :
  1. Date Completed 1990-11-07
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

1976519

DOI: Digital Object Identifier

10.1007/BF01959533

Related Literature

SNS
PICO Info
in preparation
Languages

English

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