[Clinical evaluation of bunazosin hydrochloride for the treatment of voiding disturbances due to neurogenic bladder--a double-blind study].

Author: AsoY, HonmaY, KoyanagiT, MaruA, MiyakeK, OrikasaS, ShimazakiJ, SomaF, TogashiM, YasudaK

Paper Details 
Original Abstract of the Article :
The therapeutic utility of bunazosin hydrochloride was evaluated by a multi-center (67 hospitals) double-blind controlled study in patients who complained of voiding disturbances due to neurogenic bladder. For means of comparison, bethanechol chloride and placebo were used as reference drugs. Bunazo...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1979900

データ提供:米国国立医学図書館(NLM)

Bunazosin Hydrochloride: A Promising Treatment for Neurogenic Bladder

This research delves into the realm of urological disorders, focusing on the use of bunazosin hydrochloride to treat voiding disturbances associated with neurogenic bladder. Neurogenic bladder is a condition where nerve damage affects bladder function, leading to difficulty in emptying the bladder. The researchers conducted a multi-center, double-blind, controlled study to evaluate the efficacy and safety of bunazosin hydrochloride compared to bethanechol chloride and placebo.

Bunazosin Hydrochloride Shows Promise

The study found that bunazosin hydrochloride effectively improved objective findings in patients with neurogenic bladder, including a significant decrease in residual urine volume and an increase in average flow rate. While subjective symptom improvement was not statistically different among the treatment groups, bunazosin hydrochloride showed a significantly lower rate of deterioration compared to bethanechol chloride.

A New Avenue for Neurogenic Bladder Treatment

The study highlights the potential of bunazosin hydrochloride as a valuable treatment option for neurogenic bladder. It offers a promising approach to addressing the challenges associated with this condition, potentially improving bladder function and quality of life for affected individuals.

Dr. Camel's Conclusion

Imagine a camel navigating a sandy path, seeking a way to cross a challenging terrain. Bunazosin hydrochloride, for neurogenic bladder patients, acts like a well-worn path, offering a more effective and less disruptive approach to managing this condition. The study suggests that bunazosin hydrochloride could provide a significant benefit for those struggling with neurogenic bladder.
Date :
  1. Date Completed 1991-02-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1979900

DOI: Digital Object Identifier

1979900

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PICO Info
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Languages

Japanese

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