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The impact of chronic bupropion on plasma cotinine and on the subjective effects of ad lib smoking: a randomized controlled trial in unmotivated smokers.

Author: BustoUsoa, FarvoldenPeter, HussainSarwar, SelbyPeter, ZackMartin, ZawertailoLaurie

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Bupropion, a medication for smoking cessation, decreased plasma cotinine levels and increased post-smoking satiety in unmotivated smokers. It did not affect the smokers' response to conditioned smoking-related cues.
Paper Details　
Original Abstract of the Article :
Bupropion is an efficacious non-nicotine medication for smoking cessation; however, its cessation-mediating mechanism is unclear. This randomized, placebo-controlled trial examined the effect of bupropion SR (300 mg/day for 6 weeks) on plasma cotinine and on the subjective effects of smoking in 24 c...See full text at original site
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引用元：
https://doi.org/10.1016/j.addbeh.2009.09.004

データ提供：米国国立医学図書館（NLM）

The Curious Case of Bupropion and Smoking: A Desert of Habit

This study delves into the complex world of smoking cessation, investigating the effects of the medication bupropion on the subjective experience of smoking. It’s like a journey through a desert of habit, trying to understand the power of addiction and the potential for change. The study used a randomized controlled trial to examine how bupropion affects plasma cotinine levels (a measure of nicotine exposure) and subjective responses to smoking in individuals who were not actively trying to quit.

Bupropion: A Possible Oasis in the Desert of Addiction

The results suggest that bupropion may have a subtle effect on the subjective experience of smoking, potentially reducing the pleasurable sensations associated with smoking. It’s like discovering a hidden oasis in the desert of addiction, offering a respite from the cravings and urges.

Navigating the Desert of Addiction

If you're struggling with smoking, talk to your doctor about the potential benefits of bupropion and other smoking cessation therapies. It’s like having a trusted guide to help you navigate the challenges of quitting and find the path to a smoke-free life.

Dr.Camel's Conclusion

This study sheds light on the potential of bupropion to influence the subjective experience of smoking, offering a glimpse into the complex mechanisms that drive addiction. The research underscores the importance of exploring alternative approaches to help individuals break free from harmful habits.

Date :
  1. Date Completed 2011-05-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19836144

DOI: Digital Object Identifier

10.1016/j.addbeh.2009.09.004

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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