Bromotyrosines in sputum proteins and treatment effects of terbutaline and budesonide in asthma.

Author: AldridgeRuth E, ChanTimothy, CowanJan O, HancoxRobert J, KettleAnthony J, SenthilmohanRevathy, TaylorD Robin, TownG Ian, van DalenChristine J

Paper Details 
Original Abstract of the Article :
Inhaled corticosteroids are widely used in the treatment of persistent asthma, usually combined with inhaled beta2-agonists. Previous research suggests that short-acting beta2-agonists (SABAs) may downregulate the anti-inflammatory effects of inhaled corticosteroids, thereby increasing asthma morbid...See full text at original site
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引用元:
https://doi.org/10.1016/S1081-1206(10)60536-4

データ提供:米国国立医学図書館(NLM)

The Intricate Relationship between Asthma, Corticosteroids, and Beta2-Agonists

Inhaled corticosteroids are a cornerstone of asthma treatment, often used in conjunction with inhaled beta2-agonists. However, the interaction between these two classes of medications is not fully understood. This study examines the potential for short-acting beta2-agonists (SABAs) to downregulate the anti-inflammatory effects of inhaled corticosteroids, highlighting the importance of careful medication management in asthma care.

Navigating the Asthma Treatment Landscape

The authors, like seasoned navigators charting a complex medical course, delve into the intricacies of asthma treatment, exploring the potential for SABAs to interfere with the effectiveness of inhaled corticosteroids. Their findings suggest that the combined use of these medications requires careful consideration, as the benefits of SABAs may be offset by a reduction in the anti-inflammatory effects of corticosteroids. This underscores the need for individualized treatment plans based on patient-specific needs.

Implications for Asthma Management

The study highlights the importance of optimizing asthma medication regimens to maximize benefits and minimize potential risks. It underscores the need for close collaboration between patients and healthcare professionals to monitor treatment effectiveness and adjust medications accordingly. This collaborative approach can help to ensure that patients receive the most appropriate and effective care for their asthma.

Dr.Camel's Conclusion

Just as a camel navigates the desert, we must navigate the complex landscape of asthma treatment with careful consideration. The study emphasizes the need for individualized treatment approaches and close monitoring to ensure that patients receive the best possible care and achieve optimal symptom control.

Date :
  1. Date Completed 2009-12-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

19852201

DOI: Digital Object Identifier

10.1016/S1081-1206(10)60536-4

SNS
PICO Info
in preparation
Languages

English

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