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Apoptosis induction by doxazosin and other quinazoline alpha1-adrenoceptor antagonists: a new mechanism for cancer treatment?

Author: KyprianouNatasha, MichelMartin C, VaughanTaylor B

EditorialAn article in which the editor or publisher expresses their opinion or perspective on a particular topic or issue. Its purpose is to convey a specific message or idea to the reader.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Doxazosin and related, quinazoline-based alpha(1)-adrenoceptor antagonists can induce apoptosis in prostate and various other normal, benign, smooth muscle, endothelial and malignant cells.
Paper Details　
Original Abstract of the Article :
Doxazosin and related, quinazoline-based alpha(1)-adrenoceptor antagonists can induce apoptosis in prostate and various other normal, benign, smooth muscle, endothelial and malignant cells. Such apoptosis-inducing effects occur independently of alpha(1)-adrenoceptor antagonism and typically require ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/19904527

データ提供：米国国立医学図書館（NLM）

Doxazosin and Apoptosis: A New Frontier in Cancer Treatment?

This research ventures into the exciting and complex world of cancer treatment, exploring the potential of doxazosin and related alpha(1)-adrenoceptor antagonists to induce apoptosis in various cell types. Imagine a desert landscape where cancer cells, like invasive weeds, threaten to overwhelm the healthy ecosystem. This study investigates the potential of doxazosin to act as a natural herbicide, targeting and eliminating these unwanted cells.

Harnessing the Power of Doxazosin

The study suggests that doxazosin, a medication commonly used to treat high blood pressure, can induce apoptosis in cancer cells, potentially offering a new avenue for treatment. This is like discovering a hidden oasis in the desert, providing a new source of hope and potential for fighting this formidable foe. The research highlights the need for further investigation to understand the mechanisms of doxazosin-induced apoptosis and to develop more potent and targeted treatments.

A New Era of Cancer Treatment

This research holds promise for a new era of cancer treatment, exploring the potential of repurposing existing medications to fight this devastating disease. It's like discovering a hidden treasure in the desert, revealing a new pathway for innovation and hope. The study's findings emphasize the importance of continued research to explore the potential of doxazosin and related compounds in the fight against cancer.

Dr.Camel's Conclusion

This research is a testament to the relentless pursuit of new avenues for cancer treatment, exploring the potential of doxazosin and related compounds to combat this disease. It's like discovering a hidden oasis in the desert, offering a new source of hope and promise for those battling this formidable foe. The study's findings underscore the importance of continued research to unlock the full potential of these compounds in the fight against cancer.

Date :
  1. Date Completed 2010-03-30
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

19904527

DOI: Digital Object Identifier

NIHMS862237

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Article Analysis
・Side Effects of doxazosin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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