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Meta-analysis: pre-operative infliximab treatment and short-term post-operative complications in patients with ulcerative colitis.

Author: FanD, WuK, WuQ, YangZ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Pre-operative infliximab use increased the risk of short-term post-operative complications in patients with ulcerative colitis. Subgroup analysis suggests a trend towards increased post-operative infection.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Infliximab was approved for use in ulcerative colitis in recent years. It has been debated if infliximab increases the risk of post-operative complications in patients with ulcerative colitis. AIM: To perform a meta-analysis that examines the relationship between preoperative infliximab...See full text at original site
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引用元：
https://doi.org/10.1111/j.1365-2036.2009.04204.x

データ提供：米国国立医学図書館（NLM）

Infliximab: Navigating the Desert of Postoperative Complications

Surgery, like a journey through a vast desert, can sometimes lead to complications. This meta-analysis examines the relationship between pre-operative infliximab treatment and short-term post-operative complications in patients with ulcerative colitis. The researchers reviewed five studies and analyzed data from 706 patients, exploring the impact of infliximab on post-operative infection, non-infectious complications, and overall complication rates. The results showed a trend toward an increased risk of total post-operative complications in patients who received pre-operative infliximab. However, the study found no significant association between infliximab and specific types of complications, like wound infection, sepsis, or intestinal obstruction.

A Careful Journey: The Impact of Infliximab on Postoperative Complications

This meta-analysis underscores the importance of considering the potential impact of infliximab on post-operative complications in patients with ulcerative colitis. It's like carefully navigating a vast desert, being aware of potential hazards along the way. The study's findings suggest that while infliximab may increase the overall risk of complications, it does not appear to significantly increase the risk of specific types of complications.

Understanding the Desert Landscape: Managing Postoperative Risks

The meta-analysis provides valuable insights into the potential impact of infliximab on post-operative complications in patients with ulcerative colitis. It's like a map of a vast desert, highlighting potential hazards and providing guidance for safe navigation. The study's findings suggest that while infliximab may increase the overall risk of complications, it does not appear to significantly increase the risk of specific types of complications.

Dr. Camel's Conclusion

This meta-analysis sheds light on the potential impact of infliximab on post-operative complications in patients with ulcerative colitis. It's like a journey through a vast desert, where careful navigation is crucial to avoid potential hazards. The study's findings suggest that while infliximab may increase the overall risk of complications, further research is needed to understand the specific types of complications associated with this treatment.
Date :
  1. Date Completed 2010-06-29
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

19925496

DOI: Digital Object Identifier

10.1111/j.1365-2036.2009.04204.x

SNS
PICO Info
in preparation
Languages

English

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