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Effects of nisoldipine on myocardial ischemia during exercise and during daily activity.

Author: BanaiS, BenhorinJ, BotvinS, CaspiA, GavishA, MedinaA, RogelS, TzivoniD, WeissT A, ZilbermanA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Nisoldipine improved exercise parameters and partially suppressed ischemia in patients with coronary artery disease, suggesting its effectiveness as an antiischemic agent.
Paper Details　
Original Abstract of the Article :
The antiischemic properties of nisoldipine, a dihydropyridine calcium antagonist, were assessed in a multicenter, double-blind, placebo-controlled trial by repeated exercise testing and 72-hour ambulatory electrocardiographic monitoring in 82 patients with coronary artery disease. Patients with posi...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9149(91)90891-n

データ提供：米国国立医学図書館（NLM）

Nisoldipine: A Powerful Tool in the Fight Against Myocardial Ischemia

In the vast expanse of cardiovascular health, myocardial ischemia is a treacherous oasis. This study investigates the effects of nisoldipine, a calcium antagonist, in combating this condition. The authors embarked on a rigorous journey through a multicenter, double-blind, placebo-controlled trial, using a team of 82 patients as their caravan. The goal was to determine if nisoldipine could improve exercise tolerance and reduce the frequency of ischemic episodes, much like a skilled guide leading a caravan through the challenging desert terrain.

Nisoldipine's Impact: A Powerful Ally in the Desert

The study found that nisoldipine significantly improved exercise parameters and reduced the number of ischemic episodes. While it didn't completely eliminate the threat of ischemia, it proved to be a valuable tool in navigating the treacherous landscapes of heart health, providing a more robust and resilient caravan for the journey.

Navigating the Desert of Heart Health

This research offers hope for individuals facing the challenges of myocardial ischemia. It demonstrates that nisoldipine, like a sturdy camel, can help navigate the desert of heart health, offering a more stable and secure journey for the caravan of patients.

Dr.Camel's Conclusion

Nisoldipine offers a valuable strategy in navigating the challenging desert of myocardial ischemia. It's a powerful ally in the fight against this condition, providing a more resilient and robust caravan for the journey towards a healthier heart.

Date :
  1. Date Completed 1991-04-10
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

2000786

DOI: Digital Object Identifier

10.1016/0002-9149(91)90891-n

Related Literature

Article Analysis
・Side Effects of nisoldipine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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