Drug dependence associated with triptans and ergot derivatives: a case/non-case study.

Author: Autret-LecaElisabeth, Beau-SalinasFrédérique, Bensouda-GrimaldiLamiae, CissokoHaware, Jonville-BéraAnnie Pierre

Paper Details 
Original Abstract of the Article :
INTRODUCTION: The aim of this case/non-case study was to assess and compare the risk of drug dependence associated with different migraine-specific drugs, i.e., ergot derivatives and triptans, using the French pharmacovigilance database. METHODS: Reports on drug side effects recorded in this databa...See full text at original site
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引用元:
https://doi.org/10.1007/s00228-009-0769-6

データ提供:米国国立医学図書館(NLM)

Triptans and Ergot Derivatives: A Closer Look at Drug Dependence

The quest for effective migraine treatment often leads to a complex interplay of medications, with some raising concerns about potential dependence. This study examines the risk of drug dependence associated with triptans and ergot derivatives, two commonly used classes of migraine-specific drugs. The research utilized the French pharmacovigilance database to analyze reports of drug dependence, comparing the risks associated with various triptans and ergot derivatives. The findings provide valuable insights into the potential for dependence with these medications, reminding clinicians to exercise caution and to carefully monitor patients.

Navigating the Labyrinth of Migraine Treatment

The study found that both triptans and ergot derivatives were associated with an increased risk of drug dependence, similar to benzodiazepines. The findings suggest that while these medications can be effective in treating migraines, they should be used with caution and with careful monitoring for signs of dependence. Healthcare providers should engage in open communication with patients, discussing the potential risks and benefits of these medications, and developing individualized treatment plans that prioritize both effectiveness and safety.

Navigating the Labyrinth of Migraine Treatment

The study found that both triptans and ergot derivatives were associated with an increased risk of drug dependence, similar to benzodiazepines. The findings suggest that while these medications can be effective in treating migraines, they should be used with caution and with careful monitoring for signs of dependence. Healthcare providers should engage in open communication with patients, discussing the potential risks and benefits of these medications, and developing individualized treatment plans that prioritize both effectiveness and safety.

Dr. Camel's Conclusion

The desert of migraine treatment is often marked by both hope and trepidation, as individuals seek relief from debilitating pain. This research underscores the importance of navigating the complexities of medication use, recognizing that even effective treatments can sometimes come with unintended consequences. By carefully weighing the potential benefits and risks of different medications, healthcare providers can guide their patients toward safe and effective migraine management strategies.

Date :
  1. Date Completed 2010-06-24
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20024536

DOI: Digital Object Identifier

10.1007/s00228-009-0769-6

SNS
PICO Info
in preparation
Languages

English

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