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Divalproex sodium versus placebo in the treatment of acute bipolar depression: a systematic review and meta-analysis.

Author: BondDavid J, LamRaymond W, YathamLakshmi N

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Bipolar disorder is characterized by periods of both high mood and depression, with depression being more common and causing significant disability. Divalproex is a commonly prescribed medication for bipolar disorder. While some evidence suggests that divalproex can prevent depressive episodes in the long-term, it is not often used to treat acute depression, as there is a perception that it is not very effective.
Paper Details　
Original Abstract of the Article :
Bipolar disorders (BDs) are defined by mania and hypomania, but depressions occur more frequently, last longer, and lead to significant disability. Divalproex is the most frequently prescribed anticonvulsant medication for BD. While some evidence suggests that divalproex prevents depressive episodes...See full text at original site
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引用元：
https://doi.org/10.1016/j.jad.2009.11.008

データ提供：米国国立医学図書館（NLM）

Divalproex Sodium for Acute Bipolar Depression

Bipolar disorder (BD) is a mental health condition characterized by alternating periods of mania or hypomania and depression. This research paper reviews the effectiveness of divalproex sodium, an anticonvulsant medication, in the treatment of acute bipolar depression. The authors conducted a systematic review and meta-analysis of studies on the use of divalproex sodium for acute bipolar depression. Their findings suggest that divalproex sodium may be effective in treating acute bipolar depression, but further research is needed to confirm these results. This research provides valuable insights into the potential use of divalproex sodium for the management of bipolar depression.

Divalproex Sodium: A Potential Treatment for Bipolar Depression

This research suggests that divalproex sodium may be a viable treatment option for patients with acute bipolar depression. However, more research is needed to confirm its efficacy and determine the optimal dosage for different patients. The findings of this review provide a valuable starting point for further research and clinical trials on the use of divalproex sodium for bipolar depression.

Living with Bipolar Disorder: Managing Symptoms and Seeking Treatment

If you are living with bipolar disorder, it is important to work with your doctor to develop an effective treatment plan. This research highlights the potential benefits of divalproex sodium for the management of acute bipolar depression. By working with your doctor and actively participating in your treatment, you can find the best strategies for managing your bipolar symptoms and improving your quality of life.

Dr. Camel's Conclusion

This research is like a well-worn path through the desert of bipolar disorder, offering a potential new treatment for this challenging condition. Divalproex sodium, like a trusty camel, may offer a more effective and reliable way to combat the debilitating symptoms of bipolar depression. This research is a reminder that even in the face of complex mental health challenges, we can find new ways to provide relief and improve the lives of those affected.

Date :
  1. Date Completed 2010-10-29
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

20044142

DOI: Digital Object Identifier

10.1016/j.jad.2009.11.008

Related Literature

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・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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