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The effects of benazepril, a new angiotensin-converting enzyme inhibitor, in mild to moderate essential hypertension: a multicenter study.

Author: AbrahamP A, BennettW M, BrachfeldN, GoodmanR P, HollifieldJ W, KirkendallW M, LasseterK C, LeonA S, McKenneyJ M, MoserM

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Benazepril effectively lowered blood pressure in hypertensive patients, demonstrating similar efficacy to hydrochlorothiazide.
Paper Details　
Original Abstract of the Article :
Benazepril hydrochloride is a new angiotensin-converting enzyme inhibitor. In a multicenter study, 206 patients with mild to moderate hypertension were randomized to receive benazepril at a dose of 2, 5, 10, or 20 mg, hydrochlorothiazide, 25 mg, or placebo once daily for 4 weeks. The 20 mg dosage of...See full text at original site
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引用元：
https://doi.org/10.1038/clpt.1991.36

データ提供：米国国立医学図書館（NLM）

Benazepril: A New Player in the Game of Hypertension

High blood pressure, or hypertension, is a silent but dangerous condition that affects millions of people worldwide. This study investigates the effectiveness of benazepril, a new angiotensin-converting enzyme inhibitor, in treating mild to moderate hypertension. The researchers compared the effects of different doses of benazepril to hydrochlorothiazide, a commonly used diuretic, and placebo.

Benazepril's Promise: A Balancing Act

The study found that benazepril effectively lowered blood pressure, achieving similar results to hydrochlorothiazide at the highest dose. However, at lower doses, benazepril showed no significant difference from placebo. These findings suggest that while benazepril holds potential as a treatment for hypertension, the optimal dose needs to be carefully determined for each individual patient. This is like navigating a desert landscape: finding the right balance to achieve the desired outcome requires careful observation and adjustments.

Navigating the Desert of Hypertension: Finding the Right Path

This research emphasizes the importance of personalized medicine in managing hypertension. It's like exploring a vast desert, where the path to optimal health requires careful assessment of individual needs and a tailored approach to treatment. Always consult with a qualified healthcare professional for personalized advice and guidance on managing hypertension.

Dr.Camel's Conclusion

This research highlights the importance of finding the right path for managing hypertension. It's a journey that requires careful consideration of individual needs and a balanced approach to treatment. Remember to consult with a healthcare professional for personalized advice and guidance.

Date :
  1. Date Completed 1991-04-29
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

2007326

DOI: Digital Object Identifier

10.1038/clpt.1991.36

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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