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Adverse side effects of methylphenidate among mentally retarded children with ADHD.

Author: BreauxA M, FeldmanH, GoslingA, HandenB L, McAuliffeS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Methylphenidate may increase the risk of motor tics and social withdrawal in mentally retarded children with attention deficit hyperactivity disorder.
Paper Details　
Original Abstract of the Article :
The adverse side effects of methylphenidate were evaluated in 27 children with attention deficit hyperactivity disorder and IQs of 48 to 74 who participated in a double-blind study of two doses of methylphenidate and placebo. A checklist of 13 side effects, generated from the Physician's Desk Refere...See full text at original site
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引用元：
https://doi.org/10.1097/00004583-199103000-00012

データ提供：米国国立医学図書館（NLM）

Adverse Side Effects of Methylphenidate in Mentally Retarded Children with ADHD

In the realm of child development, understanding the complexities of attention deficit hyperactivity disorder (ADHD) is a constant pursuit. This double-blind study investigates the adverse side effects of methylphenidate, a commonly prescribed medication for ADHD, in mentally retarded children.

The Challenges of ADHD Treatment in Mentally Retarded Children

The study involved 27 children with ADHD and intellectual disabilities (IQs of 48 to 74), comparing the effects of two doses of methylphenidate to a placebo. The results revealed that while methylphenidate effectively reduced symptoms like irritability, anxiety, and moodiness, it also led to the development of motor tics and severe social withdrawal in a significant number of participants.

Navigating the Risks and Benefits of ADHD Treatment

This study underscores the importance of careful consideration and personalized approaches when treating ADHD in mentally retarded children. While methylphenidate can be effective in managing symptoms, its use should be carefully monitored due to the potential for significant side effects. It's a reminder that the desert of child development is complex and multifaceted, requiring a nuanced understanding of individual needs and potential risks and benefits.

Dr.Camel's Conclusion

This study provides valuable insights into the complexities of ADHD treatment in mentally retarded children. While methylphenidate can be effective in managing symptoms, it's crucial to acknowledge the potential for serious side effects. It's a reminder that navigating the desert of child development requires a careful balance between therapeutic benefits and potential risks. As a fellow advocate for child well-being, I encourage ongoing research to further refine our understanding of ADHD treatment in this vulnerable population.

Date :
  1. Date Completed 1991-05-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2016228

DOI: Digital Object Identifier

10.1097/00004583-199103000-00012

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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