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Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans.

Author: FujitaMasatoshi, FujitaYoshiko, HayashiHideki, HorieMinoru, KakinoAkemi, KandaHiroshi, MatsudaHaruo, MatsumotoTetsuya, MitsunamiKenichi, MiwaKunihisa, NakaeIzuru, NakanishiMamoru, SatoYuko, SawamuraTatsuya, UchidaKagehiro, YoshidaAkira

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Pitavastatin, a statin, was found to reduce LDL-C, LOX-1 ligand, and triacylglycerols in patients with hypercholesterolemia. These findings suggest that pitavastatin may have beneficial effects on oxidative stress.
Paper Details　
Original Abstract of the Article :
The aim of this study was to determine the impact of pitavastatin on low-density lipoprotein cholesterol (LDL-C) and lectin-like oxidized LDL receptor-1 (LOX-1) in patients with hypercholesterolemia. Twenty-five hypercholesterolemic patients (8 male, 17 female; age 66 +/- 13, 21-80 years) who had no...See full text at original site
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引用元：
https://doi.org/10.1007/s11745-010-3402-7

データ提供：米国国立医学図書館（NLM）

Pitavastatin: A Statin with Pleiotropic Effects

High cholesterol is a major health concern, and statins are commonly prescribed to lower cholesterol levels. This research explores the potential benefits of [pitavastatin], a statin drug, beyond its cholesterol-lowering effects. It's like discovering a hidden treasure in the desert, a valuable resource with unexpected benefits.

The study examined the impact of [pitavastatin] on various biomarkers, including [lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1)] in patients with high cholesterol. The researchers analyzed the [changes in these biomarkers] after treatment with [pitavastatin]. The findings suggest that [pitavastatin] may have [pleiotropic effects], offering additional health benefits beyond its cholesterol-lowering properties.

Pitavastatin: Beyond Cholesterol Control

The study found that [specific findings regarding the effects of pitavastatin on biomarkers]. This suggests that [implication of the findings] . It's like discovering that a single desert plant not only provides food but also has medicinal properties.

A Multifaceted Approach to Heart Health

This research underscores the potential of [pitavastatin] as a multi-faceted approach to heart health. It highlights the importance of considering the potential benefits of statins beyond their cholesterol-lowering effects. It's like recognizing the diverse benefits of a desert ecosystem, understanding that each component plays a unique role in maintaining overall health and well-being.

Dr.Camel's Conclusion

This research suggests that [pitavastatin] may offer a wider range of health benefits beyond its cholesterol-lowering properties. It's a reminder to consider the potential benefits of medications beyond their primary focus, opening new avenues for improving overall health and well-being. It's like discovering a hidden oasis in the desert, offering a multitude of resources and opportunities for those seeking a healthier journey.

Date :
  1. Date Completed 2010-06-17
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

20229124

DOI: Digital Object Identifier

10.1007/s11745-010-3402-7

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Article Analysis
・Side Effects of pitavastatin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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