Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.

Author: , BurksDavid A, CenLiyi, ChaiToby C, FitzGeraldMary P, FosterHarris E, HannoPhilip M, KrederKarl J, KusekJohn W, LandisJ Richard, LukaczEmily S, MayerRobert D, NickelJ Curtis, NybergLeroy M, PayneChristopher K, PetersKenneth M, PropertKathleen J, YangClaire C, YangWei

Paper Details 
Original Abstract of the Article :
PURPOSE: Amitriptyline is frequently used to treat patients with interstitial cystitis/painful bladder syndrome. The evidence to support this practice is derived mainly from a small, single site clinical trial and case reports. MATERIALS AND METHODS: We conducted a multicenter, randomized, double-b...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/20303115

データ提供:米国国立医学図書館(NLM)

Amitriptyline: A Potential Treatment for Interstitial Cystitis

This research investigates [the effectiveness of amitriptyline] in [treating interstitial cystitis/painful bladder syndrome (IC/PBS)]. The study uses a [multicenter, randomized, double-blind, placebo-controlled clinical trial] to compare [amitriptyline treatment] with [placebo] in [patients with IC/PBS]. The authors aimed to determine [the impact of amitriptyline] on [symptoms of IC/PBS] and assess [the potential benefits] of this medication.

Amitriptyline Shows Promise in Treating IC/PBS

The study found that [amitriptyline may be beneficial] for patients with IC/PBS, particularly those who [can achieve a daily dose of 50 mg or greater]. However, the researchers also found that [amitriptyline did not significantly improve symptoms] in all patients. This suggests that [amitriptyline may not be effective] for everyone with IC/PBS.

Living with Interstitial Cystitis: Finding the Right Treatment

Interstitial cystitis can be a challenging condition for patients. This research, like a camel navigating a desert of treatment options, highlights the importance of [finding the right treatment] for each individual. It underscores the need for [careful consideration] when prescribing amitriptyline for IC/PBS, and emphasizes the importance of [individualized treatment plans] that address patient-specific needs.

Dr.Camel's Conclusion

This research, like a camel searching for a reliable source of water in a dry desert, explores the potential of amitriptyline as a treatment for IC/PBS. While the findings suggest that amitriptyline may be helpful for some patients, it emphasizes the importance of personalized medicine and finding the right treatment for each individual.

Date :
  1. Date Completed 2010-05-06
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

20303115

DOI: Digital Object Identifier

NIHMS191671

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.