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Systemic interferon alpha-2b increases the cure rate in laser treated patients with multiple persistent genital warts: a placebo-controlled study.

Author: BjerringP, BlaakaerJ, FromE, HagdrupH, LarsenJ, ObergaardL, PetersenC S

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effectiveness of adding interferon-alpha 2b to laser treatment for persistent genital warts in 49 patients. The study found that interferon significantly increased the cure rate (52% vs 23%) compared to placebo. While interferon caused more side effects like fever, chills, and muscle aches, these were generally manageable, and only 3 out of 32 patients stopped treatment due to side effects. The study concludes that interferon-alpha 2b can be a helpful addition to laser treatment for resistant genital warts, improving cure rates despite potential side effects.
Paper Details　
Original Abstract of the Article :
Systemic treatment modalities for eradication of multiple therapy resistant genital warts are so far not available. In this study laser treated patients with multiple genital warts received postoperatively either interferon alpha-2b subcutaneously (s.c.) 5 x 10(6) IU or matching placebo three times ...See full text at original site
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引用元：
https://doi.org/10.1136/sti.67.2.99

データ提供：米国国立医学図書館（NLM）

Systemic Interferon Alpha-2b: A Potential Booster for Genital Wart Treatment

The [Treatment of Genital Warts] landscape is ever-evolving, seeking new and effective therapies for this persistent condition. This placebo-controlled study investigates the efficacy of systemic interferon alpha-2b in patients with multiple persistent genital warts who have undergone laser treatment. The study found that interferon alpha-2b significantly increased the cure rate compared to placebo. While side effects were more common in the interferon group, they were generally manageable, and only a small number of patients discontinued treatment due to adverse effects. The findings suggest that systemic interferon alpha-2b could be a valuable adjunct to laser treatment for persistent genital warts.

Interferon Alpha-2b: A Potential Ally in the Fight Against Genital Warts

The study's findings are promising, suggesting that interferon alpha-2b could be a useful tool in the treatment of persistent genital warts. The drug's ability to enhance the cure rate following laser treatment offers a potential solution for individuals struggling with this condition.

Navigating the Path to Genital Wart Resolution

This research shines a light on the potential of systemic interferon alpha-2b in treating persistent genital warts. The findings suggest that combining this therapy with laser treatment could be a promising approach for achieving a cure.

Dr. Camel's Conclusion

Genital warts can be a stubborn and persistent problem, like a desert that refuses to yield its secrets. This study offers a glimmer of hope, suggesting that interferon alpha-2b could be a valuable tool in the fight against these persistent lesions. Just as a camel adapts to the harsh desert environment, we must continue to explore new avenues in the quest for effective genital wart treatments.

Date :
  1. Date Completed 1991-06-27
  2. Date Revised 2019-05-03
Further Info :

Pubmed ID

2032716

DOI: Digital Object Identifier

10.1136/sti.67.2.99

Related Literature

Article Analysis
・Effective treatment of genital warts
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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