Systemic isotretinoin in the treatment of rosacea - doxycycline- and placebo-controlled, randomized clinical study.

Author: Blume-PeytaviUlrike, GollnickHarald, HauptmannPetra, MeyerKarl-Gustav, PoppGeorg, SebastianMichael, SzabóEörs Lāszlō, WillersChristoph, ZwingersThomas, von der WethRenate

Paper Details 
Original Abstract of the Article :
BACKGROUND: Systemic isotretinoin has been known for decades to be effective in the treatment of severe forms of rosacea, but it must be used off-label because of the lack of evidence-based data. PATIENTS AND METHODS: 573 patients with rosacea subtype II and III received one of three different dosa...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1610-0387.2010.07345.x

データ提供:米国国立医学図書館(NLM)

Systemic Isotretinoin: A Desert Oasis for Rosacea Relief?

Rosacea, a common skin condition, is like a stubborn desert sandstorm, leaving skin red, inflamed, and uncomfortable. This study explores the effectiveness of systemic isotretinoin as a treatment for rosacea, comparing it to doxycycline and placebo. The researchers conduct a randomized, double-blind clinical trial to determine the optimal dosage and efficacy of isotretinoin.

The study's findings indicate that systemic isotretinoin, like a refreshing desert oasis, might offer a promising solution for rosacea. Isotretinoin, at a dosage of 0.3 mg/kg, demonstrated significant superiority to placebo and non-inferiority to doxycycline in reducing lesions and improving skin condition. The researchers also note that isotretinoin displayed a similar safety profile to its use in acne treatment. This suggests that isotretinoin might be a valuable alternative to oral antibiotics for treating rosacea.

Isotretinoin: A New Oasis for Rosacea Sufferers

This study provides compelling evidence for the effectiveness of systemic isotretinoin as a treatment for rosacea. It offers a new oasis of relief for those struggling with this common and often frustrating skin condition.

Rosacea: Finding Relief in the Desert

This research is a valuable step forward in understanding and treating rosacea. It suggests that isotretinoin could be a promising new weapon in the battle against this stubborn skin condition, providing a much-needed oasis of relief for those affected.

Dr.Camel's Conclusion

This study provides evidence that systemic isotretinoin is an effective and well-tolerated treatment option for rosacea. It offers a potential new oasis of relief for those suffering from this condition, providing hope for improved skin health and well-being.

Date :
  1. Date Completed 2010-12-02
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

20337772

DOI: Digital Object Identifier

10.1111/j.1610-0387.2010.07345.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.