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Adrenal function in asthmatic children treated with inhaled budesonide.

Author: BisgaardH, Damkjaer NielsenM, OsterballeO, PedersenS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Budesonide, an inhaled topical steroid, did not cause significant adrenal suppression in asthmatic children, demonstrating a favorable ratio between topical and systemic effects.
Paper Details　
Original Abstract of the Article :
The effect of the inhaled topical steroid budesonide on adrenal function was evaluated in 33 children (aged 7-15 years) with moderate bronchial asthma. The trial was designed as a prospective single-blind study of the effect of budesonide in daily doses of 200 microgram through 400 microgram to 800 ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1651-2227.1991.tb11836.x

データ提供：米国国立医学図書館（NLM）

Inhaled Budesonide: A Safe and Effective Treatment for Asthma

Asthma is a chronic respiratory condition that affects millions of people worldwide. This study investigated the effects of inhaled budesonide, a topical steroid, on adrenal function in children with moderate bronchial asthma. The researchers conducted a prospective single-blind study to assess the impact of different doses of inhaled budesonide on the production of cortisol, a hormone produced by the adrenal glands. They aimed to determine if inhaled budesonide caused any significant suppression of adrenal function.

Inhaled Budesonide: Minimal Impact on Adrenal Function

The study found no significant dose-related suppression of adrenal function in children with moderate bronchial asthma treated with inhaled budesonide. This finding is reassuring, suggesting that inhaled budesonide is a safe and effective treatment option for asthma, with minimal systemic effects.

Managing Asthma Effectively

This study underscores the importance of choosing asthma medications that minimize potential side effects while effectively managing the disease. Inhaled budesonide emerges as a safe and effective treatment option, offering a balance between efficacy and safety.

Dr. Camel's Conclusion

Asthma is a chronic condition that can feel like a desert wind, constantly blowing dust into your lungs. Inhaled budesonide, like a calming oasis, provides relief from asthma symptoms without significantly affecting your body's natural balance. This research reinforces the importance of finding effective and safe treatments for asthma, allowing individuals to breathe easier and live fuller lives.

Date :
  1. Date Completed 1991-06-25
  2. Date Revised 2019-08-20
Further Info :

Pubmed ID

2035313

DOI: Digital Object Identifier

10.1111/j.1651-2227.1991.tb11836.x

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Article Analysis
・Effects of budesonide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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