Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa.

Author: BecqueminMarie-Helene, BouhemadBelaïd, GirardiCassio, Le NaourGilles, LouchahiKamel, LuQin, MarquetteCharles-Hugo, PetitjeanOlivier, RoubyJean-Jacques, WalletFrédéric, ZhangMao

Paper Details 
Original Abstract of the Article :
Emergence of multidrug-resistant strains in intensive care units has renewed interest in colistin, which often remains the only available antimicrobial agent active against resistant Pseudomonas aeruginosa. The aim of this study is to compare lung tissue deposition and antibacterial efficiency betwe...See full text at original site
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引用元:
https://doi.org/10.1007/s00134-010-1879-4

データ提供:米国国立医学図書館(NLM)

Colistin Delivery for Pneumonia: Finding the Right Path Through the Desert of Resistance

This study explores the effectiveness of colistin, a last-resort antibiotic, in treating pneumonia caused by Pseudomonas aeruginosa, a bacteria known for its resistance to many antibiotics. Imagine a caravan facing a fierce sandstorm, with only a limited supply of water – that's the situation faced by patients with multidrug-resistant infections. This research compares the effectiveness of nebulized and intravenous colistin delivery in combating this challenging infection.

Colistin Delivery: A Battle Against Resistance

The study investigated the lung tissue deposition and antibacterial efficiency of colistin delivered through nebulization and intravenous administration in piglets with pneumonia caused by Pseudomonas aeruginosa. It's like testing two different strategies for navigating a sandstorm, with each approach aiming to reach the oasis of recovery. The results of this study can help guide clinical decision-making regarding the most effective way to administer colistin for patients with this serious infection.

Colistin: A Weapon in the Fight Against Bacterial Resistance

This study highlights the importance of research into new and effective ways to treat multidrug-resistant infections. It's like discovering a new oasis in the vast desert of antibiotic resistance. By exploring different delivery methods and understanding their effectiveness, we can improve the chances of success in treating these challenging infections. The study underscores the need for continued research and innovation in the fight against bacterial resistance.

Dr.Camel's Conclusion

This study delves into the intricate world of colistin delivery for pneumonia caused by Pseudomonas aeruginosa. It's like navigating a treacherous desert, where finding the right route to combat bacterial resistance is crucial for survival. The research compares the effectiveness of different delivery methods, highlighting the importance of optimizing treatment strategies for these challenging infections. The quest for new solutions to antibiotic resistance continues, and this study offers valuable insights into this critical area of medical research.

Date :
  1. Date Completed 2010-10-08
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20397007

DOI: Digital Object Identifier

10.1007/s00134-010-1879-4

Related Literature

SNS
PICO Info
in preparation
Languages

English

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