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Effect of Raloxifene on all-cause mortality.

Author: CauleyJane A, CoxDavid A, CummingsSteven R, GradyDeborah, MitlakBruce H, SongJingli, StockJohn L

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Raloxifene, a selective estrogen receptor modulator, can help reduce osteoporosis and breast cancer risk. However, it may increase the risk of venous thromboembolism and stroke in women with heart disease. Further research is needed to assess its overall risk and benefit.
Paper Details　
Original Abstract of the Article :
Raloxifene, a selective estrogen receptor modulator, reduces osteoporosis and invasive breast cancer risk but increases risk for venous thromboembolism and fatal stroke in women with or at high risk for coronary heart disease. To assess the risk/benefit of raloxifene as a preventative treatment, we ...See full text at original site
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引用元：
https://doi.org/10.1016/j.amjmed.2009.12.018

データ提供：米国国立医学図書館（NLM）

Raloxifene: Weighing the Risks and Benefits

Raloxifene, a selective estrogen receptor modulator, has shown promise in reducing osteoporosis and breast cancer risk. However, like many medications, it also carries potential side effects. This study delves into the overall risks and benefits of raloxifene, specifically analyzing its effect on all-cause mortality. The researchers gathered data from various studies to assess the impact of raloxifene on mortality rates.

Raloxifene: A Complex Risk-Benefit Profile

The study found that while raloxifene can offer some benefits, it may also increase the risk of venous thromboembolism (blood clots) and fatal stroke, particularly in women with or at high risk for coronary heart disease. The researchers conclude that the overall risk-benefit profile of raloxifene needs careful consideration on an individual basis.

Health Implications and Everyday Applications

This study highlights the importance of a comprehensive approach to managing health risks. While raloxifene can be a valuable tool for some individuals, it's essential to carefully assess the potential risks and benefits before starting any medication.

Dr.Camel's Conclusion

The desert of medical decision-making is often filled with uncertainty. This study reminds us that every medication has its own unique landscape of risks and benefits. We need to carefully weigh the pros and cons, just as a traveler in the desert would carefully consider the path ahead. With careful assessment and guidance, we can navigate this complex terrain and make informed choices about our health.

Date :
  1. Date Completed 2010-04-29
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

20399327

DOI: Digital Object Identifier

10.1016/j.amjmed.2009.12.018

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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