Immunogenicity and safety study of Indirab: a Vero cell based chromatographically purified human rabies vaccine.

Author: AshwathnarayanaDoddabele Hanumanthaiah, MadhusudanaShampur Narayan, MadhusudhanSanthosh Kumar, MahendraBangalore Jayakrishna, MohanKrishna, RavishHaradanahalli Shankariah, SampathGadey, SudarshanMysore Kalappa, UllasThankappan P

Paper Details 
Original Abstract of the Article :
A chromatographically purified Vero cell rabies vaccine, Indirab manufactured by Bharat Biotech International Limited, Hyderabad, India was subjected to safety and immunogenicity studies by both intramuscular and intradermal routes of administration in parallel with a reference vaccine, Verorab. A P...See full text at original site
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引用元:
https://doi.org/10.1016/j.vaccine.2010.03.064

データ提供:米国国立医学図書館(NLM)

Evaluating the Safety and Immunogenicity of a New Rabies Vaccine

Rabies is a deadly disease, and vaccination is crucial for preventing its spread. This article presents a comprehensive study evaluating the safety and immunogenicity of a new rabies vaccine, Indirab, manufactured by Bharat Biotech International Limited. The study compares Indirab to a reference vaccine, Verorab, using different administration routes (intramuscular and intradermal) in pre-exposure, post-exposure, and simulated post-exposure settings. The authors concluded that Indirab is as safe and immunogenic as Verorab.

Indirab: A Safe and Effective Rabies Vaccine

This study provides strong evidence for the safety and efficacy of Indirab, a new rabies vaccine. The authors found that Indirab met WHO standards for immunogenicity and safety when administered both intramuscularly and intradermally. This could be a significant advancement in rabies vaccination, offering an alternative to existing vaccines and ensuring a wider availability of this critical public health tool.

Think About It Like a Desert Oasis

Imagine a desert oasis, providing a haven for weary travelers. Similarly, a safe and effective vaccine, like Indirab, offers protection from the deadly threat of rabies. The study demonstrates that Indirab is a reliable source of protection against this devastating disease, potentially saving lives and preventing suffering.

Dr.Camel's Conclusion

This study provides valuable information for public health professionals and researchers working to prevent rabies. It confirms the safety and efficacy of Indirab, a new rabies vaccine, offering a reliable alternative to existing vaccines and potentially improving access to this vital preventive measure.

Date :
  1. Date Completed 2010-08-27
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

20403351

DOI: Digital Object Identifier

10.1016/j.vaccine.2010.03.064

Related Literature

SNS
PICO Info
in preparation
Languages

English

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